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Hazard identification of pyrogenic synthetic amorphous silica (NM-203) after sub-chronic oral exposure in rat: A multitarget approach
- Source :
- Food and Chemical Toxicology, Food and Chemical Toxicology, Elsevier, 2020, 137, pp.111168. ⟨10.1016/j.fct.2020.111168⟩
- Publication Year :
- 2019
-
Abstract
- International audience; Food additive E551 consists of synthetic amorphous silica (SAS), comprising agglomerates and aggregates of primary particles in the nanorange (
- Subjects :
- Male
E551
Administration, Oral
Food additive
Hazard characterization
Nanomaterials
No observed adverse effect level
Sex-related effects
Sub-chronic toxicity
Hazard analysis
nanomatériau
Rats, Sprague-Dawley
toxicité
Sub chronic
0303 health sciences
Chemistry
04 agricultural and veterinary sciences
General Medicine
Nanomaterial
Silicon Dioxide
040401 food science
3. Good health
Subchronic toxicity
food safety
Liver
[SDV.TOX]Life Sciences [q-bio]/Toxicology
Female
Amorphous silica
toxicology
Silicon
food.ingredient
Risk Assessment
03 medical and health sciences
0404 agricultural biotechnology
food
adverse effect
Animals
sécurité des aliments
030304 developmental biology
Sex-related effect
additif alimentaire
No-Observed-Adverse-Effect Level
toxicity
toxicologie
Nanostructures
Chemical engineering
exposure
Food Additives
Biomarkers
Food Science
Subjects
Details
- ISSN :
- 18736351 and 02786915
- Volume :
- 137
- Database :
- OpenAIRE
- Journal :
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- Accession number :
- edsair.doi.dedup.....3a71b792bb8f2849fb0731fea7988b62
- Full Text :
- https://doi.org/10.1016/j.fct.2020.111168⟩