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The n10 component of the ocular vestibular-evoked myogenic potential (oVEMP) is distinct from the R1 component of the blink reflex
- Source :
- Clinical Neurophysiology, 120(8), 1567-1576. ELSEVIER IRELAND LTD
- Publication Year :
- 2009
-
Abstract
- Objective: Bone-conducted vibration (BCV) in the midline at the hairline (Fz), results in short latency potentials recorded by surface electrodes beneath the eyes - the ocular vestibular-evoked myogenic potential (oVEMP). The early negative component of the oVEMP, n10, is due to vestibular stimulation, however it is similar to the early R1 component of the blink reflex. Here we seek to dissociate n10 from R1. Methods: Surface potentials were recorded from the infraorbital electromyogram of 10 healthy subjects, 6 patients with bilateral vestibular loss, 2 with unilateral vestibular loss, 4 with facial palsy and 3 with facial and vestibular nerve lesions on the same side. BCV was delivered at Fz, the inion, the glabella or the supra-orbital ridge using a tendon hammer or a bone-conduction vibrator. Results: Onset latencies of the n10 evoked by taps at Fz or inion were significantly shorter than the R1 components of blink responses to supraorbital and glabellar stimuli. Upward gaze increased the amplitude of The n10 was absent bilaterally in patients with bilateral vestibular loss and beneath the contralesional eye in patients with unilateral vestibular loss, but in both these groups of patients R1 was preserved. In severe facial palsy the R1 component was absent or delayed and attenuated ipsilesionally, but n10 was preserved bilaterally. In subjects with unilateral facial and vestibular nerve lesions (Herpes Zoster of the facial and vestibulocochlear nerves) the dissociation was complete - the ipsilesional R1 was absent or attenuated whereas the ipsilesional n10 was preserved. Conclusions: n10 is distinguished from R1 by its earlier onset, laterality, modulation by gaze position and dissociation in patient groups. Significance: The n10 component evoked by BCV at Fz is not the R1 component of the blink reflex. (C) 2009 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
- Subjects :
- Male
STIMULATION
Eye Movements
genetic structures
Audiology
Otolith
Functional Laterality
Blink reflex
VESTIBULOOCULAR REFLEX
NERVE
Corneal reflex
Evoked Potentials
Vestibular system
SOUND
Ocular vestibular-evoked myogen potential
MIDLINE FOREHEAD
oVEMP
Middle Aged
Facial nerve
Sensory Systems
Facial paralysis
Vestibular
Neurology
Vestibular Diseases
Female
medicine.symptom
Psychology
Adult
medicine.medical_specialty
Vestibular evoked myogenic potential
Facial Paralysis
Young Adult
Physiology (medical)
medicine
Reaction Time
Cranial nerve disease
Humans
FZ
Aged
VEMP
Blinking
Electromyography
Vestibular Function Tests
Vestibular nerve
medicine.disease
R1
Bone conduction
Acoustic Stimulation
Oculomotor Muscles
BONE-CONDUCTED VIBRATION
Neurology (clinical)
Vestibulo–ocular reflex
RESPONSES
Subjects
Details
- Language :
- English
- ISSN :
- 13882457
- Volume :
- 120
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Clinical Neurophysiology
- Accession number :
- edsair.doi.dedup.....3a8abe3c6175beb31a3998fbcd1844c2
- Full Text :
- https://doi.org/10.1016/j.clinph.2009.06.008