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Re‐Thinking Re‐Synching in Left Ventricular Assist Device Recipients
Re‐Thinking Re‐Synching in Left Ventricular Assist Device Recipients
- Source :
- Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
- Publication Year :
- 2018
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2018.
-
Abstract
- Many patients with heart failure continue cardiac resynchronization therapy (CRT) after continuous flow left ventricular assist device (CF-LVAD) implant. We report the first multicenter study to assess the impact of CRT on clinical outcomes in CF-LVAD patients.Analysis was performed on 488 patients (58±13 years, 81% male) with an implantable cardioverter defibrillator (ICD) (n=223) or CRT-D (n=265) who underwent CF-LVAD implantation at 5 centers from 2007 to 2015. Effects of CRT on mortality, hospitalizations, and ventricular arrhythmia incidence were compared against CF-LVAD patients with an ICD alone. Baseline differences were noted between the 2 groups in age (60±12 versus 55±14,In this large, multicenter CF-LVAD cohort, continued CRT was not associated with improved survival, hospitalizations, incidence of ventricular arrhythmia and ICD therapies, and was related to a significantly higher number of pulse generator changes.
- Subjects :
- Adult
Male
medicine.medical_specialty
Time Factors
medicine.medical_treatment
Population
Cardiac resynchronization therapy
cardiac resynchronization therapy
030204 cardiovascular system & hematology
Prosthesis Design
Amiodarone
Ventricular Function, Left
Prosthesis Implantation
03 medical and health sciences
0302 clinical medicine
Risk Factors
Internal medicine
left ventricular assist device
medicine
Humans
030212 general & internal medicine
education
amiodarone
Aged
Retrospective Studies
Heart Failure
education.field_of_study
business.industry
Incidence
Editorials
Arrhythmias, Cardiac
Middle Aged
Remodeling
United States
Editorial
Treatment Outcome
Ventricular assist device
Cardiology
Female
Heart-Assist Devices
Cardiology and Cardiovascular Medicine
business
Catheter Ablation and Implantable Cardioverter-Defibrillator
medicine.drug
Subjects
Details
- ISSN :
- 20479980
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Journal of the American Heart Association
- Accession number :
- edsair.doi.dedup.....3a9cb249e8ce1fb0400d14d481a25463
- Full Text :
- https://doi.org/10.1161/jaha.118.009591