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Factors influencing cognitive function in patients with atrial fibrillation: a cross-sectional clinical study
- Source :
- The Journal of International Medical Research, Journal of International Medical Research, Vol 47 (2019)
- Publication Year :
- 2019
- Publisher :
- SAGE Publications, 2019.
-
Abstract
- Background The factors that influence cognitive function in patients with atrial fibrillation (AF) remain unclear. Methods This study involved an AF group and control group (normal sinus rhythm) of 150 patients each. Cognitive function was assessed with the adjusted Mini-Mental State Examination (MMSEadj) score and Memory and Executive Screening (MES) score. The relationship between cognitive function and the CHA2DS2VASc score was analyzed. Subgroup analysis was performed according to stroke history. Clinical factors affecting the MMSE score were screened by logistic regression analysis. Results Baseline data were similar between the two groups. The MMSEadj and MES scores were significantly lower in the AF than control group; the mean MMSEadj score in the AF non-stroke subgroup and control non-stroke subgroup was 26.2 ± 2.7 and 27.9 ± 2.0, respectively. In non-stroke patients with AF, the MMSEadj and MES scores were negatively correlated with the CHA2DS2VASc score. Factors significantly influencing the MMSE score in these patients were age, education, smoking history, NT-proB-type natriuretic peptide, hemoglobin, and anticoagulation. Conclusion AF is associated with cognitive dysfunction regardless of stroke history. High CHA2DS2VASc scores are associated with impaired cognitive function. Factors influencing cognitive function in non-stroke patients with AF are age, education, smoking history, NT-proB-type natriuretic peptide, hemoglobin, and anticoagulation.
- Subjects :
- Male
Medicine (General)
medicine.medical_specialty
Clinical Research Reports
Memory and Executive Screening
CHA2DS2VASc score
030204 cardiovascular system & hematology
Biochemistry
Clinical study
Executive Function
03 medical and health sciences
R5-920
Cognition
0302 clinical medicine
Memory
Risk Factors
Internal medicine
medicine
Humans
In patient
anticoagulation
Normal Sinus Rhythm
cognitive function
Aged
Mini–Mental State Examination
medicine.diagnostic_test
business.industry
Biochemistry (medical)
Atrial fibrillation
Cell Biology
General Medicine
Mental Status and Dementia Tests
medicine.disease
Cross-Sectional Studies
Logistic Models
Case-Control Studies
Multivariate Analysis
Cardiology
Mini-Mental State Examination
Female
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 14732300 and 03000605
- Volume :
- 47
- Database :
- OpenAIRE
- Journal :
- Journal of International Medical Research
- Accession number :
- edsair.doi.dedup.....3ab582a8e1b113d1845faa3f1019991e