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Can Ratio of Neutrophil-Tolymphocyte Count and Erythrocyte Sedimentation Rate in Diabetic Foot Infection Predict Osteomyelitis and/or Amputation?
- Source :
- Hematology Reports; Volume 9; Issue 1; Pages: 19-21, Hematology Reports, Vol 9, Iss 1 (2017), Hematology Reports
- Publication Year :
- 2017
- Publisher :
- MDPI AG, 2017.
-
Abstract
- The aim of this study was to search for any relations between the neutrophil-tolymphocyte ratio (NLR) and the development of osteomyelitis and the need for amputation in patients with diabetic foot infection (DFI). All data included DFI patients who were hospitalized in our Infectious Diseases Clinic between 2012 and 2015 and who were classified according to International Classification Disease Code System. 75 patients were analyzed in the study. The DFI patients were stratified into 3 groups of whom had amputation procedure, whom had only debridement/drainage procedure and whom had any surgery procedure. Sidac post hoc analysis was used to perform the effects of NLR, C-reactive protein, erythrocyte sedimentation rate and glycosylated hemoglobin on the surgery procedure status. The DFI patients were also stratified into two another separate group for another analysis to search for the effect of NLR values on the development of osteomyelitis. The mean value of NLR in the amputated patients’ group (15.7 ± 10.3 was significantly higher than those with debridement procedure (9.9 ± 5.6) and those without any surgery (6.0 ± 2.8) (p = 0.001). NLR values were also found significantly higher in patients with osteomyelitis in the second analysis (p = 0.004). In this study, the NLR was found to have a predictive value on the development of osteomyelitis and on the progression to amputation in patients with DFI.
- Subjects :
- medicine.medical_specialty
Lymphocyte
medicine.medical_treatment
030204 cardiovascular system & hematology
Article
03 medical and health sciences
0302 clinical medicine
Surgery procedure
amputation
Post-hoc analysis
medicine
In patient
030212 general & internal medicine
Neutrophil to lymphocyte count
medicine.diagnostic_test
lcsh:RC633-647.5
business.industry
Osteomyelitis
fungi
osteomyelitis
lcsh:Diseases of the blood and blood-forming organs
Hematology
medicine.disease
Diabetic foot
Surgery
medicine.anatomical_structure
Amputation
Erythrocyte sedimentation rate
diabetic foot infection
business
neutrophil to lymphocyte count
Subjects
Details
- ISSN :
- 20388330
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Hematology Reports
- Accession number :
- edsair.doi.dedup.....3acfac974816cd1fa96d556a0db3b39a
- Full Text :
- https://doi.org/10.4081/hr.2017.6981