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Efficacy and safety of PulseRider for treatment of wide-necked intracranial aneurysm—A systematic review and meta-analysis
- Source :
- Interv Neuroradiol
- Publication Year :
- 2020
- Publisher :
- SAGE Publications, 2020.
-
Abstract
- Objective PulseRider is a novel self-expanding nickel-titanium (nitinol) stent for treatment of wide-necked aneurysms, which is commonly located at the arterial branches in the brain. This systematic review and meta-analysis aims to assess the efficacy and safety of PulseRider for treatment of wide-necked intracranial aneurysm. Method We performed a systematic literature search on articles that evaluate the efficacy and safety of PulseRider-assisted coiling of the wide-necked aneurysm from several electronic databases. The primary endpoint was adequate occlusion, defined as Raymond-Roy Class I + Raymond-Roy Class II upon immediate angiography and at six-month follow-up. Results There were a total of 157 subjects from six studies. The rate of adequate occlusion on immediate angiography was 90% (95% CI, 85%–94%) and 91% (95% CI, 85%–96%) at six-month follow-up. Of these, Raymond-Roy Class I can be observed in 48% (95% CI, 41%–56%) of aneurysms immediately after coiling, and 64% (95% CI, 55%–72%) of aneurysms on six-month follow-up. Raymond-Roy Class II was found in 30% (95% CI, 23%–37%) of aneurysms immediately after coiling, and 25% (17–33) after six-month follow-up. Complications occur in 5% (95% CI, 1%–8%) of the patients. There were three intraoperative aneurysm rupture, three thrombus formation, three procedure-related posterior cerebral artery strokes, one vessel dissection, and one delayed device thrombosis. There was no procedure/device-related death. Conclusions PulseRider-assisted coiling for treatment of patients with wide-necked aneurysm reached 90% adequate occlusion rate that rises up to 91% at sixth month with 5% complication rate.
- Subjects :
- medicine.medical_specialty
business.industry
medicine.medical_treatment
Endovascular Procedures
Cerebral Aneurysms
Stent
Intracranial Aneurysm
Aneurysm, Ruptured
medicine.disease
Embolization, Therapeutic
030218 nuclear medicine & medical imaging
03 medical and health sciences
Treatment Outcome
0302 clinical medicine
Aneurysm
Wide necked aneurysm
Meta-analysis
medicine
Humans
Stents
Radiology
business
030217 neurology & neurosurgery
Retrospective Studies
Subjects
Details
- ISSN :
- 23852011 and 15910199
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Interventional Neuroradiology
- Accession number :
- edsair.doi.dedup.....3b3259d90ca03c71c8cd2ea95d746477
- Full Text :
- https://doi.org/10.1177/1591019920940521