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Managing female pelvic floor disorders: a medical device review and appraisal
- Source :
- Interface Focus
- Publication Year :
- 2019
- Publisher :
- The Royal Society, 2019.
-
Abstract
- Pelvic floor disorders (PFDs) will affect most women during their lifetime. Sequelae such as pelvic organ prolapse, stress urinary incontinence, chronic pain and dyspareunia significantly impact overall quality of life. Interventions to manage or eliminate symptoms from PFDs aim to restore support of the pelvic floor. Pessaries have been used to mechanically counteract PFDs for thousands of years, but do not offer a cure. By contrast, surgically implanted grafts or mesh offer patients a more permanent resolution but have been in wide use within the pelvis for less than 30 years. In this perspective review, we provide an overview of the main theories underpinning PFD pathogenesis and the animal models used to investigate it. We highlight the clinical outcomes of mesh and grafts before exploring studies performed to elucidate tissue level effects and bioengineering considerations. Considering recent turmoil surrounding transvaginal mesh, the role of pessaries, an impermanent method, is examined as a means to address patients with PFDs.
- Subjects :
- Pessary
medicine.medical_specialty
030232 urology & nephrology
Biomedical Engineering
Biophysics
Psychological intervention
Bioengineering
Urinary incontinence
Biochemistry
Pelvic Floor Disorders
Biomaterials
03 medical and health sciences
0302 clinical medicine
Quality of life
medicine
Pelvis
030219 obstetrics & reproductive medicine
Pelvic floor
business.industry
Chronic pain
Articles
medicine.disease
medicine.anatomical_structure
Physical therapy
medicine.symptom
business
Biotechnology
Subjects
Details
- ISSN :
- 20428901 and 20428898
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Interface Focus
- Accession number :
- edsair.doi.dedup.....3b3379451f7889027034045afcd73ec7
- Full Text :
- https://doi.org/10.1098/rsfs.2019.0014