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Telomerase Regulation from Beginning to the End

Authors :
Chantal Autexier
Hélène Jeanne Bensoussan
Deanna Elise MacNeil
Source :
Genes, Genes, Vol 7, Iss 9, p 64 (2016)
Publication Year :
2016

Abstract

The vast body of literature regarding human telomere maintenance is a true testament to the importance of understanding telomere regulation in both normal and diseased states. In this review, our goal was simple: tell the telomerase story from the biogenesis of its parts to its maturity as a complex and function at its site of action, emphasizing new developments and how they contribute to the foundational knowledge of telomerase and telomere biology.

Details

ISSN :
20734425
Volume :
7
Issue :
9
Database :
OpenAIRE
Journal :
Genes
Accession number :
edsair.doi.dedup.....3b97650086f2c0585d1488e1a7fe6ee5