Rearrangements and racemisation during the synthesis of l-serine derived oxazolidin-2-ones

Authors :: Stephen G. Davies
Steven D. Bull
Edward D. Savory
Sean P. Bew
David J. Watkin
Source :: Tetrahedron. 58:9387-9401
Publication Year :: 2002
Publisher :: Elsevier BV, 2002.
Abstract: The propensity for N-Boc-4-hydroxymethyl-oxazolidin-2-ones to undergo rapid O-O and N-O carbonyl transfer makes these L-serine derived chiral auxiliaries unsuitable for attachment to polymers. © 2002 Elsevier Science Ltd. All rights reserved.

Subjects :: chemistry.chemical_classification
Serine
chemistry
Stereochemistry
organic chemicals
Organic Chemistry
Drug Discovery
heterocyclic compounds
L serine
Polymer
Biochemistry

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