An endoperoxide-containing covalent organic framework as a singlet oxygen reservoir for cancer therapy

Authors :: Fei Lu
Limeng Pan
Tong Wu
Wei Pan
Wen Gao
Na Li
Bo Tang
Source :: Chemical Communications. 58:11013-11016
Publication Year :: 2022
Publisher :: Royal Society of Chemistry (RSC), 2022.
Abstract: An endoperoxide-containing COF was constructed to deliver extracellular singlet oxygen into cancer cells to realize light- and oxygen-independent oxidative damage for cancer therapy.

Subjects :: Oxygen
Porphyrins
Cycloaddition Reaction
Singlet Oxygen
Neoplasms
Materials Chemistry
Metals and Alloys
Ceramics and Composites
General Chemistry
Metal-Organic Frameworks
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials

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