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Supraclavicular lymph node incisional biopsies have no influence on the prognosis of advanced non-small cell lung cancer patients: a retrospective study

Authors :
Qiang Nie
Feng Li
Wei Deng
Yi-Long Wu
Chong-Rui Xu
Ning Zhao
Wen-Zhao Zhong
Fei-Yu Niu
Hong-Hong Yan
Jin-Ji Yang
Xue-Ning Yang
Qiuyi Zhang
Hui-Wen Sun
Ri-Qiang Liao
Song Dong
Source :
World Journal of Surgical Oncology
Publication Year :
2017
Publisher :
Springer Science and Business Media LLC, 2017.

Abstract

Background Supraclavicular lymph node (SCLN) biopsies play an important role in diagnosing and staging lung cancer. However, not all patients with SCLN metastasis can have a complete resection. It is still unknown whether SCLN incisional biopsies affect the prognosis of non-small cell lung cancer (NSCLC) patients. Methods Patients who were histologically confirmed to have NSCLC with SCLN metastasis were enrolled in the study from January 2007 to December 2012 at Guangdong Lung Cancer Institute. The primary endpoint was OS, and the secondary endpoints were complications and local recurrence/progression. Results Two hundred two consecutive patients who had histologically confirmed NSCLC with SCLN metastasis were identified, 163 with excisional and 39 with incisional biopsies. The median OS was not significantly different between the excisional (10.9 months, 95% CI 8.7–13.2) and incisional biopsy groups (10.1 months, 95% CI 6.3–13.9), P = 0.569. Multivariable analysis showed that an Eastern Cooperative Oncology Group (ECOG) performance status (PS) ≥2 (HR = 2.75, 95% CI 1.71–4.38, P

Details

ISSN :
14777819
Volume :
15
Database :
OpenAIRE
Journal :
World Journal of Surgical Oncology
Accession number :
edsair.doi.dedup.....3c49d9144da063ca62798c9eef997ca0
Full Text :
https://doi.org/10.1186/s12957-016-1064-5