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Geographic patterns of inversion polymorphisms in a wild African rodent, Mastomys erythroleucus
- Source :
- Heredity, Heredity, Nature Publishing Group, 2010, 104 (4), pp.378-386. ⟨10.1038/hdy.2009.119⟩
- Publication Year :
- 2010
- Publisher :
- HAL CCSD, 2010.
-
Abstract
- Correspondance: gauthier.dobigny@ird.fr; International audience; By suppressing recombination and reducing gene flow, chromosome inversions favor the capture and protection of advantageous allelic combinations, leading to adaptive polymorphisms. However, studies in non-model species remain scarce. Here we investigate the distribution of inversion polymorphisms in the multimammate rat Mastomys erythroleucus in West Africa. More than 270 individuals from 52 localities were karyotyped using G-bands and showed widespread polymorphisms involving four chromosome pairs. No significant deviations from Hardy–Weinberg equilibrium were observed either through space or time, nor were differences retrieved in viability or sex contribution between cytotypes. The distribution of chromosomal variation, however, showed perfect congruence with that of mtDNAbased phylogeographic clades. Thus, inversion diversity patterns in M. erythroleucus appeared more related to historical and/or demographic processes than to climatebased adaptive features. Using cross-species chromosome painting and G-banding analyses to identify homologous chromosomes in related out-group species, we proposed a phylogenetic scenario that involves ancestral-shared polymorphisms and subsequent lineage sorting during expansion/ contraction of West African savannas. Our data suggest that long-standing inversion polymorphisms may act as regions in which adaptation genes may accumulate (nucleation model)
- Subjects :
- Male
0106 biological sciences
Chad
Rodent
LINEAGE SORTING
ZOO-FISH
Inversion (geology)
chromosome evolution
Animals, Wild
ANCESTRAL POLYMORPHISM
phylogeography
010603 evolutionary biology
01 natural sciences
lineage sorting
Chromosome Painting
polymorphism
PHYLOGEOGRAPHY
03 medical and health sciences
Gene Frequency
ancestral
biology.animal
Genetics
Animals
Cameroon
Mastomys erythroleucus
POLYMORPHISME ANCESTRAL
Phylogeny
Genetics (clinical)
030304 developmental biology
0303 health sciences
Polymorphism, Genetic
Geography
biology
CHROMOSOME EVOLUTION
Zoo-FISH
biology.organism_classification
Africa, Western
Chromosome Inversion
RAT
Female
Murinae
GENETIQUE DES POPULATIONS
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0018067X
- Database :
- OpenAIRE
- Journal :
- Heredity, Heredity, Nature Publishing Group, 2010, 104 (4), pp.378-386. ⟨10.1038/hdy.2009.119⟩
- Accession number :
- edsair.doi.dedup.....3c6625bca6d6efdc63d64e61401abecf