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Quantitative assessment of valvular function after cardiac transplantation by pulsed doppler echocardiography
- Source :
- The American Journal of Cardiology. 73:1197-1201
- Publication Year :
- 1994
- Publisher :
- Elsevier BV, 1994.
-
Abstract
- In 31 patients who had undergone cardiac orthotopic transplantation, valvular regurgitation was studied by echocardiographic and pulsed Doppler over 2 years. The first week after cardiac transplantation, transplant recipients had an increase in the severity of tricuspid, mitral (group II), and aortic regurgitation, as well as a greater number of simultaneously regurgitating valves when compared with those in a group of 60 normal subjects of similar age to heart donors: transplant recipients, trivalvular regurgitation 48% (95% confidence interval [CI] 30 to 66) vs control group, 5% (CI 1 to 13; p0.001). Moderate-severe tricuspid regurgitation (TR) was the most frequent occurrence (55%, CI 36 to 73) followed by pulmonary (PR) (42%, CI 25 to 61), moderate mitral (MR) (32%, CI 15 to 51), and mild aortic (AR) (23%, CI 10 to 43) regurgitation. These regurgitations were asymptomatic at rest except for TR. TR was associated with right-sided heart failure in 76% of patients in the early postoperative period and controlled with diuretic drugs. This regurgitation correlated with persistence of post-transplant pulmonary hypertension (r = 0.6) and was not related to pulmonary hypertension before cardiac transplant. There was also no relation found between donor ischemia time or episodes of cardiac rejection.(ABSTRACT TRUNCATED AT 250 WORDS)
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Heart Ventricles
Hypertension, Pulmonary
Group ii
Blood Pressure
Regurgitation (circulation)
Orthotopic transplantation
Internal medicine
Ventricular Pressure
Quantitative assessment
Humans
Medicine
Pulmonary Wedge Pressure
Heart valve
business.industry
Mitral Valve Insufficiency
Pulsed Doppler Echocardiography
Middle Aged
Heart Valves
Echocardiography, Doppler
Pulmonary Valve Insufficiency
Tricuspid Valve Insufficiency
Confidence interval
Surgery
Transplantation
medicine.anatomical_structure
Echocardiography
Ventricular Function, Right
cardiovascular system
Cardiology
Heart Transplantation
Female
Cardiology and Cardiovascular Medicine
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 00029149
- Volume :
- 73
- Database :
- OpenAIRE
- Journal :
- The American Journal of Cardiology
- Accession number :
- edsair.doi.dedup.....3c854c297f91f9f3b652518bc25acd6e
- Full Text :
- https://doi.org/10.1016/0002-9149(94)90181-3