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Nutraceutical potential of polyphenolic fractions from Annurca apple (M. pumila Miller cv Annurca)
- Source :
- Food Chemistry. 140:614-622
- Publication Year :
- 2013
- Publisher :
- Elsevier BV, 2013.
-
Abstract
- The capacities of polyphenolic extracts from Annurca apple peel and flesh to inhibit the glucose and cholesterol uptake by HepG2 cells were evaluated, and compared with those of other conventional cultivars, such as Red Delicious (RD), Pink Lady (PL), Fuji (F) and Golden Delicious (GD). RD peels exhibited the best hypoglycaemic effects, while Annurca flesh appeared the most active in reducing cell cholesterol uptake among the cultivars tested. The influence of the apple polyphenolic extracts on the cell proliferation and oxidative stress was also evaluated. Particularly, RD, Annurca and PL peels decreased proliferation by a 62.5%, 48.0% and 37.5%, respectively, probably due to their prooxidant capacity. Conversely, flesh extracts appeared more protective of cells than peels: Annurca and RD, particularly, proved to be able of increasing proliferation by a 32.2% and 11.1%, respectively, probably due to their capacity of reducing cell physiological radical levels of a 33.3% and 19.9%, respectively.
- Subjects :
- Carbohydrate metabolism
medicine.disease_cause
Analytical Chemistry
Nutraceutical
Botany
Pink lady
medicine
Humans
Cultivar
Food science
Cell Proliferation
Plant Extracts
Chemistry
Flesh
fungi
Polyphenols
food and beverages
Biological Transport
Hep G2 Cells
General Medicine
Oxidative Stress
Glucose
Polyphenol
Fruit
Malus
Hepg2 cells
Dietary Supplements
Oxidative stress
Food Science
Subjects
Details
- ISSN :
- 03088146
- Volume :
- 140
- Database :
- OpenAIRE
- Journal :
- Food Chemistry
- Accession number :
- edsair.doi.dedup.....3cb2b9045563cfa60345299ed05de13f