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Impact of Antimalarial Adherence on Mortality Among Patients With Newly Diagnosed Systemic Lupus Erythematosus: A <scp>Population‐Based</scp> Cohort Study
- Source :
- Arthritis Care & Research. 74:1089-1097
- Publication Year :
- 2022
- Publisher :
- Wiley, 2022.
-
Abstract
- OBJECTIVE To assess the association of antimalarials (AM) adherence with premature mortality among incident systemic lupus erythematosus (SLE) patients. METHODS All patients with incident SLE and incident AM use in British Columbia, Canada, between January 1997 and March 2015 were identified using the provincial administrative databases. Follow-up started on the first day of having both SLE and AM. The outcome was all-cause mortality. An adherence measure, proportion of days covered (PDC), was calculated and categorized as adherent (PDC≥0.90), non-adherent (0
- Subjects :
- medicine.medical_specialty
British Columbia
business.industry
Proportional hazards model
Inverse probability weighting
Confounding
Hazard ratio
Newly diagnosed
Middle Aged
Lower risk
Medication Adherence
Cohort Studies
Antimalarials
Population based cohort
Rheumatology
Healthcare utilization
Risk Factors
Internal medicine
Humans
Lupus Erythematosus, Systemic
Medicine
business
Proportional Hazards Models
Subjects
Details
- ISSN :
- 21514658 and 2151464X
- Volume :
- 74
- Database :
- OpenAIRE
- Journal :
- Arthritis Care & Research
- Accession number :
- edsair.doi.dedup.....3d7c06b6cf9f60f23e44310c8a909b36
- Full Text :
- https://doi.org/10.1002/acr.24550