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A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia
- Source :
- Schizophrenia research. 125(2-3)
- Publication Year :
- 2010
-
Abstract
- Objective There is considerable interest in cognitive remediation for schizophrenia. Our study aimed to evaluate, in a large sample of patients with schizophrenia, the interest of a computer-assisted cognitive remediation program on cognitive performances of patients as well as in clinical and functional outcome. Method Seventy-seven patients with remitted schizophrenia were randomly assigned to 14 2-hours individual sessions of computer-assisted cognitive remediation (n = 39) or a control condition (n = 38). Remediation was performed using RehaCom ® software. Four procedures were chosen to train four cognitive functions involved in different stages of the information processing: attention/concentration, working memory, logic, and executive functions. Primary outcomes were remediation exercise metrics, neuropsychological composites (episodic memory, working memory, attention, executive functioning, and processing speed), clinical and community functioning measures. Results Cognitive performances concerning Attention/vigilance, verbal working memory and verbal learning memory and reasoning/problem solving improved significantly in the remediation condition when no difference was reported in the control condition between the 2 assessments. However, there were no significant benefits of cognitive remediation on non-verbal working memory and learning and speed of processing or functional outcome measures. Conclusions Cognitive remediation for people with schizophrenia was effective in improving performance, but the benefits of training did not generalize to functional outcome measures. Long term follow-up studies are needed to confirm the maintenance of such improvements.
- Subjects :
- Adult
Male
media_common.quotation_subject
Neuropsychological Tests
Verbal learning
Double-Blind Method
Humans
Remedial Teaching
Episodic memory
Biological Psychiatry
media_common
Working memory
Neuropsychology
Cognition
Executive functions
Psychiatry and Mental health
Cognitive remediation therapy
Schizophrenia
Female
Schizophrenic Psychology
France
Psychology
Cognition Disorders
Vigilance (psychology)
Clinical psychology
Computer-Assisted Instruction
Follow-Up Studies
Subjects
Details
- ISSN :
- 15732509
- Volume :
- 125
- Issue :
- 2-3
- Database :
- OpenAIRE
- Journal :
- Schizophrenia research
- Accession number :
- edsair.doi.dedup.....3dd1a0ffc160e6c6f84cf22012cf9001