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A modified 3D printer as a hybrid bioprinting-electrospinning system for use in vascular tissue engineering applications
- Source :
- Fazal, F, Diaz Sanchez, F J, Waqas, M, Koutsos, V, Callanan, A & Radacsi, N 2021, ' A modified 3D printer as a hybrid bioprinting-electrospinning system for use in vascular tissue engineering applications ', Medical Engineering and Physics, vol. 94, pp. 52-60 . https://doi.org/10.1016/j.medengphy.2021.06.005
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- There is a high demand for small diameter vascular grafts having mechanical and biological properties similar to that of living tissues. Tissue-engineered vascular grafts using current methods have often failed due to the mismatch of mechanical properties between the implanted graft and living tissues. To address this limitation, a hybrid bioprinting-electrospinning system is developed for vascular tissue engineering applications. The setup is capable of producing layered structure from electrospun fibres and cell-laden hydrogel. A Creality3D Ender 3D printer has been modified into a hybrid setup having one bioprinting head and two electrospinning heads. Fortus 250mc and Flashforge Creator Pro 3D printers were used to print parts using acrylonitrile butadiene styrene (ABS) and polylactic acid (PLA) polymers. An Arduino mega 2560 and a Ramps 1.4 controller board were selected to control the functions of the hybrid bioprinting setup. The setup was tested successfully to print a tubular construct around a rotating needle.
- Subjects :
- Materials science
Electrospinning
Tissue Engineering
Tissue Scaffolds
business.industry
Acrylonitrile butadiene styrene
Bioprinting
technology, industry, and agriculture
Biomedical Engineering
Biophysics
Vascular tissue engineering
3D printing
Hydrogels
Layered structure
3d printer
chemistry.chemical_compound
Polylactic acid
chemistry
Biological property
Printing, Three-Dimensional
business
Biomedical engineering
Subjects
Details
- ISSN :
- 13504533
- Volume :
- 94
- Database :
- OpenAIRE
- Journal :
- Medical Engineering & Physics
- Accession number :
- edsair.doi.dedup.....3dfb13a0d77401b4c0fd34e82f939f6b