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Heterogeneity of the pharmacologic treatment of allergic rhinitis in Europe based on MIDAS and OTCims platforms

Authors :
Torsten Zuberbier
Julia Saueressig
Joaquim Mullol
Glenis Scadding
João Fonseca
G. Walter Canonica
Eric Van Ganse
Claus Bachert
Bolesław Samoliński
Olga Lourenço
Oliver Pfaar
Philippe Devillier
Ann-Kathrin Stroh
Wienczyslawa Czarlewski
Jean Bousquet
Ludger Klimek
Elísio Costa
Piotr Kuna
Detlef Schroder-Bernhardi
Victoria Cardona
Sophie Scheire
Nhan Pham Thi
Institut Català de la Salut
[Bousquet J] Charité Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Berlin, Germany. Department of Dermatology and Allergy, Comprehensive Allergy Center, Berlin Institute of Health, Berlin, Germany. University Hospital Montpellier, Montpellier, France. MACVIA-France, Montpellier, France. [Schröder-Bernhardi D] IQVIA Consumer Health, Frankfurt, Germany. [Bachert C] Upper Airways Research Laboratory, ENT Dept, Ghent University Hospital, Ghent, Belgium. International Airway Research Center, First Affiliated Hospital Guangzou, Sun Yat-sen University, Guangzou, China. Division of ENT Diseases, CLINTEC, Karolinska Institutet, Stockholm, Sweden. Department of ENT Diseases, Karolinska University Hospital, Stockholm, Sweden. [Canonica GW] Personalized Medicine Asthma, & Allergy Clinic-Humanitas University & Research Hospital, IRCCS-Milano, Milano, Italy. [Cardona V] Servei d’Al·lergologia
Servei de Medicina Interna, Vall d'Hebron Hospital Universitari, Barcelona, Spain. ARADyAL Research Network, Barcelona, Spain. [Costa EM] UCIBIO, REQUINTE, Faculty of Pharmacy and Competence Center on Active and Healthy Ageing of University of Porto (Porto4Ageing), Porto, Portugal
Vall d'Hebron Barcelona Hospital Campus
uBibliorum
Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)
Charité - UniversitätsMedizin = Charité - University Hospital [Berlin]
Berlin Institute of Health (BIH)
Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR)
Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA)
Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO)
IQVIA
Ghent University Hospital
Sun Yat-Sen University [Guangzhou] (SYSU)
Karolinska Institutet [Stockholm]
Karolinska University Hospital [Stockholm]
IRCCS Istituto Nazionale dei Tumori [Milano]
Vall d'Hebron University Hospital [Barcelona]
Unidade de Ciencias Biomoleculares Aplicadas (UCIBIO)
Requimte
Universidade do Porto = University of Porto-Departamento de Química (DQ)
Faculdade de Ciências e Tecnologia = School of Science & Technology (FCT NOVA)
Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Faculdade de Ciências e Tecnologia = School of Science & Technology (FCT NOVA)
Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Universidade do Porto = University of Porto-Departamento de Química (DQ)
Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)-Universidade Nova de Lisboa = NOVA University Lisbon (NOVA)
Hôpital Foch [Suresnes]
Universidade do Porto = University of Porto
University Medical Center [Mainz]
Medical University of Łódź (MUL)
University of Beira Interior [Portugal] (UBI)
Centro de Investigación Biomédica en Red Enfermedades Respiratorias (CIBERES)
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
Universitat de Barcelona (UB)
Philipps Universität Marburg = Philipps University of Marburg
Institut de Recherche Biomédicale des Armées (IRBA)
Medical University of Warsaw - Poland
University College of London [London] (UCL)
Health Service and Performance Research (HESPER)
Université Claude Bernard Lyon 1 (UCBL)
Université de Lyon-Université de Lyon
Retiveau, Nolwenn
Source :
Scientia, CLINICAL AND EXPERIMENTAL ALLERGY, Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos), Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação, instacron:RCAAP, Clinical and Experimental Allergy, Clinical and Experimental Allergy, 2021, 51 (8), pp.1033-1045. ⟨10.1111/cea.13884⟩
Publication Year :
2021

Abstract

Rinitis al·lèrgica; Costos; Medicaments Rinitis alérgica; Costos; Medicamentos Allergic rhinitis; Costs; Medications Background The practice of allergology varies widely between countries, and the costs and sales for the treatment of rhinitis differ depending on practices and health systems. To understand these differences and their implications, the rhinitis market was studied in some of the EU countries. Methods We conducted a pharmaco-epidemiological database analysis to assess the medications that were being prescribed for allergic rhinitis in the years 2016, 2017 and 2018. We used the IQVIA platforms for prescribed medicines (MIDAS®—Meaningful Integration of Data, Analytics and Services) and for OTC medicines (OTC International Market Tracking—OTCims). We selected the five most important markets in the EU (France, Germany, Italy, Poland and Spain). Results Intranasal decongestants were excluded from the analyses because they are rarely prescribed for allergic rhinitis. For both Standard Units (SU) and costs, France is leading the other countries. In terms of SU, the four other countries are similar. For costs, Poland is lower than the three others. However, medication use differs largely. For 2018, in SU, intranasal corticosteroid is the first treatment in Poland (70.0%), France (51.3%), Spain (51.1%) and Germany (50.3%), whereas the Italian market is dominated by systemic antihistamines (41.4%) followed by intranasal corticosteroids (30.1%). Results of other years were similar. Discussion There are major differences between countries in terms of rhinoconjunctivitis medication usage.

Subjects

Subjects :
0301 basic medicine
Allergy
IMPACT
Database analysis
Medications
costs
MESH: Allergy and Immunology
Medication
Other subheadings::Other subheadings::/drug therapy [Other subheadings]
Allergic rhinitis
0302 clinical medicine
medications
MESH: Anti-Allergic Agents
Anti-Allergic Agents
Medicine and Health Sciences
Medicine
Immunology and Allergy
[SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/Allergology
Practice Patterns, Physicians'
health care economics and organizations
International market
Medication use
Units
enfermedades respiratorias::enfermedades nasales::rinitis::rinitis alérgica [ENFERMEDADES]
Medicaments - Prescripció - Europa
Europe
MESH: Rhinitis, Allergic
[SDV.IMM]Life Sciences [q-bio]/Immunology
preparados farmacéuticos::medicamentos por prescripción [COMPUESTOS QUÍMICOS Y DROGAS]
localizaciones geográficas::Europa (continente) [DENOMINACIONES GEOGRÁFICAS]
MIDAS
[SDV.IMM.ALL] Life Sciences [q-bio]/Immunology/Allergology
Rinitis - Tractament - Europa
Healthcare system
medicine.medical_specialty
[SDV.IMM] Life Sciences [q-bio]/Immunology
Immunology
Respiratory Tract Diseases::Nose Diseases::Rhinitis::Rhinitis, Allergic [DISEASES]
Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores]
Geographic Locations::Europe [GEOGRAPHICALS]
Eu countries
PERSON-CENTERED CARE
Pharmacological treatment
03 medical and health sciences
units
Environmental health
Allergy and Immunology
MANAGEMENT
Humans
Pharmaceutical Preparations::Prescription Drugs [CHEMICALS AND DRUGS]
MESH: Humans
allergic rhinitis
OTC Medicines
business.industry
PATHWAYS
Al·lèrgia - Tractament - Europa
AIR-POLLUTION
medicine.disease
Rhinitis, Allergic
Costs
030104 developmental biology
030228 respiratory system
Analytics
Family medicine
MESH: Practice Patterns, Physicians'
ASTHMA
MESH: Europe
business

Details

ISSN :
13652222 and 09547894
Volume :
51
Issue :
8
Database :
OpenAIRE
Journal :
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES
Accession number :
edsair.doi.dedup.....3e53262fcf69591ff2eeb47ff1266ffe
Full Text :
https://doi.org/10.1111/cea.13884⟩