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Synthesis of Bis-Glyoxylamide Peptidomimetics Derived from Bis-N-acetylisatins Linked at C5 by a Methylene or Oxygen Bridge
- Source :
- Molecules, Volume 24, Issue 23
- Publication Year :
- 2019
- Publisher :
- MDPI AG, 2019.
-
Abstract
- The bis-glyoxylamide peptidomimetics have been synthesized from bis-N-acetylisatins linked at C5 by ring-opening with alcohols, amines, and amino acid methyl ester hydrochlorides. X-ray images of single crystals of bis-glyoxylamide peptidomimetics have been obtained.
- Subjects :
- Isatin
Models, Molecular
Indoles
Peptidomimetic
Antimicrobial peptides
Pharmaceutical Science
Article
glyoxylamides
Analytical Chemistry
antimicrobial peptides
chemistry.chemical_compound
N-acetylisatins
Drug Discovery
Amines
Amino Acids
Physical and Theoretical Chemistry
Methylene
chemistry.chemical_classification
Molecular Structure
X-Rays
Organic Chemistry
quorum sensing
Esters
Combinatorial chemistry
Amino acid
Oxygen
Quorum sensing
chemistry
Chemistry (miscellaneous)
peptidomimetics
Alcohols
Molecular Medicine
Oxygen bridge
Methane
Subjects
Details
- ISSN :
- 14203049
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....3f0bd3119222c4118eccebaeb845d53b
- Full Text :
- https://doi.org/10.3390/molecules24234343