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Age-adjusted Charlson Comorbidity Index (ACCI) is a significant factor for predicting survival after radical gastrectomy in patients with gastric cancer
- Source :
- BMC Surgery, BMC Surgery, Vol 19, Iss 1, Pp 1-11 (2019)
- Publication Year :
- 2019
- Publisher :
- BioMed Central, 2019.
-
Abstract
- Introduction To assess the ability of the Age-Adjusted Charlson Comorbidity Index (ACCI) to predict survival after radical gastrectomy in patients with gastric cancer (GC). Method Data from patients with GC who underwent radical gastrectomy from January 2008 to December 2012 in Fujian Medical University Union Hospital were retrospectively analyzed. Patients were categorized into either high ACCI group or low ACCI group based on the effect of ACCI on long-term GC prognosis. 1:1 propensity score matching (PSM) was used to reduce confounding bias. To further analyze the impact of ACCI on the long-term prognosis of patients after radical gastrectomy, a nomogram was built based on the Cox proportional hazards regression model. Results A total of 1476 patients were included in the analysis. After PSM, there was no statistically significant differences in tumor location, tumor size and tumor stage between low ACCI group (429 cases) and high ACCI group (429 cases) (all P > 0.05). Before and after PSM, the incidence of postoperative complications in high ACCI group was significantly higher than that in low ACCI group (P
- Subjects :
- Adult
medicine.medical_specialty
medicine.medical_treatment
Age adjustment
lcsh:Surgery
Outcomes
030230 surgery
TNM staging system
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Postoperative Complications
Gastrectomy
Risk Factors
Stomach Neoplasms
Internal medicine
Medicine
Humans
Risk factor
Aged
Neoplasm Staging
Proportional Hazards Models
Retrospective Studies
ACCI
Gastric adenocarcinoma
business.industry
Incidence (epidemiology)
Incidence
Confounding
General Medicine
lcsh:RD1-811
Nomogram
Middle Aged
Prognosis
Surgery
Survival Rate
Nomograms
030220 oncology & carcinogenesis
Propensity score matching
Multivariate Analysis
business
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 14712482
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- BMC Surgery
- Accession number :
- edsair.doi.dedup.....3f351c940d33ccebe66b36562c1d2a45