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α2cDel322-325 and β1Arg389 Adrenergic Polymorphisms Are Not Associated With Reduced Left Ventricular Ejection Fraction or Increased Left Ventricular Volume
- Source :
- Journal of the American College of Cardiology. (2):274-276
- Publisher :
- American College of Cardiology Foundation. Published by Elsevier Inc.
-
Abstract
- To the Editor Polymorphisms in adrenergic receptors are potential risk factors for developing systolic heart failure (HF) presumably via modulation of sympathetic nervous system activity ([1][1]). Two such polymorphisms (α2cDel322-325 and β1Arg389) appear to have adverse synergistic effects, with
- Subjects :
- Adult
Male
Cardiac output
medicine.medical_specialty
Sympathetic nervous system
Adrenergic receptor
Genotype
Cardiac Output, Low
Adrenergic
Sensitivity and Specificity
White People
Muscle hypertrophy
Cohort Studies
Ventricular Dysfunction, Left
Receptors, Adrenergic, alpha-2
Internal medicine
Medicine
Humans
Receptor
Alleles
Heart Failure
Ejection fraction
Polymorphism, Genetic
business.industry
Stroke Volume
Middle Aged
medicine.disease
Black or African American
medicine.anatomical_structure
Heart failure
Cardiology
Female
Hypertrophy, Left Ventricular
Receptors, Adrenergic, beta-1
business
Cardiology and Cardiovascular Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 07351097
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of the American College of Cardiology
- Accession number :
- edsair.doi.dedup.....3f6a1fb66f78538534e6e76f1e8b1821
- Full Text :
- https://doi.org/10.1016/j.jacc.2006.10.016