Cost-effectiveness of initial antiretroviral treatment administered as single vs. multiple tablet regimens with the same or different components

Authors :: Josep M. Gatell
Sébastien Gallien
Elisa de Lazzari
Bonaventura Clotet
Josep M. Llibre
Daniel Podzamczer
Juan González-García
Pere Domingo
Jean-Michel Molina
Arkaitz Imaz
Source :: Enfermedades Infecciosas y Microbiologia Clinica, r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol, instname, ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Publication Year :: 2016
Abstract: Objective: To evaluate the efficiency of single-tablet regimens (STR) and multiple-tablet regimens (MTR) with exactly the same or different components. Methods: A study was conducted on HIV-1-infected antiretroviral-naive patients from 6 Spanish or French centers, who were started on treatment with STR-Atripla (R), or the same components separately (MTR-SC), or a different MTR (MTR-Other). Effectiveness was measured as percentage of HIV-RNA = 100.000 copies/mL. The duration of the assigned treatment was longer for STR-Atripla (R) (P

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