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Safety and side effects of transperineal prostate biopsy without antibiotic prophylaxis
- Source :
- Urologic oncology. 39(11)
- Publication Year :
- 2020
-
Abstract
- Study aims To investigate safety and side effects of transperineal prostate biopsy without antibiotic prophylaxis. Secondary aim was to identify whether the number of cores influenced the occurrence of complications. Patients and methods A cohort of 184 patients undergoing perineal prostate biopsy without antibiotic prophylaxis from 2015 to 2017 was analyzed retrospectively. On average, 41 cores were taken via two perineal skin punctures. Demographic and clinical data were obtained from patients´ electronic medical records. Binary logistic regression was performed to identify predictors for complications with the following covariates: age, prostate specific antigen (PSA), prostate volume, Prostate Imaging Reporting and Data System score, history of prostatitis, therapeutic anticoagulation, risk factors for urinary tract infection, surgery duration, and the number of biopsy cores. Furthermore, we calculated chi-squared tests with post hoc analyses for differences in the occurrence of complications between quartiles of the above-mentioned parameters. Results The overall complication rate was 10.8% (20/185). Out of 20, 19 (95 %) complications were ≤ grade 2 according to the Clavien-Dindo classification. There were two cases of afebrile urinary tract infection, and no patient developed fever or sepsis. Acute urinary retention was reported in 10 patients (5.4 %). The total number of cores was not associated to infectious complications or acute urinary retention rates. Conclusions Transperineal prostate biopsy without antibiotic prophylaxis is a safe procedure. Neither postoperative fever nor sepsis occurred. An increased number of cores through two skin punctures was not associated with more complications.
- Subjects :
- Image-Guided Biopsy
Male
medicine.medical_specialty
Prostate biopsy
Urology
030232 urology & nephrology
Prostatitis
03 medical and health sciences
Postoperative fever
0302 clinical medicine
Prostate
Biopsy
medicine
Humans
Antibiotic prophylaxis
Aged
Retrospective Studies
medicine.diagnostic_test
business.industry
Urinary retention
Prostatic Neoplasms
Antibiotic Prophylaxis
Middle Aged
medicine.disease
Surgery
Prostate-specific antigen
medicine.anatomical_structure
Oncology
030220 oncology & carcinogenesis
medicine.symptom
business
Subjects
Details
- ISSN :
- 18732496
- Volume :
- 39
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Urologic oncology
- Accession number :
- edsair.doi.dedup.....3f803fb4b0f910f3f48b6e1f5f536832