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Genome-Scale Analysis of Homologous Genes among Subgenomes of Bread Wheat (Triticum aestivum L.)
- Source :
- International Journal of Molecular Sciences, Vol 21, Iss 3015, p 3015 (2020), International Journal of Molecular Sciences, Volume 21, Issue 8
- Publication Year :
- 2020
- Publisher :
- MDPI AG, 2020.
-
Abstract
- Determining the distribution and correspondence of genome-scale homologous genes in wheat are effective ways to uncover chromosome rearrangement that has occurred during crop evolution and domestication, which can contribute to improvements in crop breeding. High-resolution and comprehensive analysis of the wheat genome by the International Wheat Genome Sequencing Consortium (IWGSC) revealed a total of 88,733 high-confidence homologous genes of four major types (1:1:1, 1:1:0, 0:1:1 and 1:0:1) among the A, B and D subgenomes of wheat. This data was used to compare homologous gene densities among chromosomes, clarify their distribution and correspondence relationship, and compare their functional enrichment. The average density of 1:1:1 homologous genes was about 10 times more than the density of the other three types of homologous genes, although the homologous gene densities of the various chromosomes were similar within each homologous type. Three regions of exceptional density were detected in 1:1:1 homologous genes, the isolate peak on the tail of chromosome 4A, and the desert regions at the start of chromosome 7A and 7D. The correspondence between homologous genes of the wheat subgenomes demonstrated translocation between the tail segments of chromosome 4A and 5A, and the inversion of the segment of original 5A and 7B into the tail of 4A. The homologous genes on the inserting segments of 5A and 7B to 4A were highly enriched in nitrogen, primary metabolite and small molecular metabolism processes, compared with genes on other regions of the original 4A chromosome. This study provides a refined genome-scale reference of homologous genes for wheat molecular research and breeding, which will help to broaden the application of the wheat genome and can be used as a template for research on other polyploid plants.
- Subjects :
- 0106 biological sciences
0301 basic medicine
gene distribution
bread wheat
Chromosomal translocation
Chromosomal rearrangement
Biology
Genes, Plant
01 natural sciences
Genome
subgenome
Catalysis
DNA sequencing
Article
Inorganic Chemistry
Evolution, Molecular
lcsh:Chemistry
03 medical and health sciences
Polyploid
Homologous chromosome
Physical and Theoretical Chemistry
Molecular Biology
Gene
genome
lcsh:QH301-705.5
Spectroscopy
Conserved Sequence
Genetics
Organic Chemistry
Chromosome
Computational Biology
food and beverages
General Medicine
Genomics
homologous gene
Computer Science Applications
030104 developmental biology
Gene Ontology
lcsh:Biology (General)
lcsh:QD1-999
Multigene Family
Genome, Plant
010606 plant biology & botany
Genome-Wide Association Study
Subjects
Details
- Language :
- English
- ISSN :
- 16616596 and 14220067
- Volume :
- 21
- Issue :
- 3015
- Database :
- OpenAIRE
- Journal :
- International Journal of Molecular Sciences
- Accession number :
- edsair.doi.dedup.....3f92e83c1a4f2f2f7f2a85356f76d316