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Should variants of unknown significance (VUS) be disclosed to patients in cardiogenetics or not; only in case of high suspicion of pathogenicity?

Authors :
Saskia N. van der Crabben
Stellan Mörner
Anna C. Lundström
Jenni Jonasson
Hennie Bikker
Ahmad S. Amin
Annika Rydberg
Arthur A. M. Wilde
Human Genetics
ACS - Amsterdam Cardiovascular Sciences
ACS - Pulmonary hypertension & thrombosis
ARD - Amsterdam Reproduction and Development
Cardiology
ACS - Heart failure & arrhythmias
Human genetics
Source :
van der Crabben, S N, Mörner, S, Lundström, A C, Jonasson, J, Bikker, H, Amin, A S, Rydberg, A & Wilde, A A M 2022, ' Should variants of unknown significance (VUS) be disclosed to patients in cardiogenetics or not; only in case of high suspicion of pathogenicity? ', European Journal of Human Genetics, vol. 30, no. 11, pp. 1208-1210 . https://doi.org/10.1038/s41431-022-01173-z, European journal of human genetics, 30(11), 1208-1210. Nature Publishing Group, European Journal of Human Genetics, 30(11), 1208-1210. Nature Publishing Group
Publication Year :
2022

Details

Language :
English
ISSN :
10184813
Volume :
30
Issue :
11
Database :
OpenAIRE
Journal :
European journal of human genetics
Accession number :
edsair.doi.dedup.....3fa4015b6489c8399c8d1ee3808e327b
Full Text :
https://doi.org/10.1038/s41431-022-01173-z