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Effects of repetitive transcranial magnetic stimulation on neuropathic pain: A systematic review and meta-analysis
- Source :
- Neuroscience & Biobehavioral Reviews. 132:130-141
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- Neuropathic pain (NP) is a chronic pain condition caused by lesion or disease of the somatosensory nervous system. Repetitive transcranial magnetic stimulation (rTMS) is a neuroregulatory tool that uses pulsed magnetic fields to modulate the cerebral cortex. This review aimed to ascertain the therapeutic effect of rTMS on NP and potential factors regulating the therapeutic effect of rTMS. Database search included Web of Science, Embase, Pubmed, and Cochrane Library from inception to July 2021. Eligible studies included randomized controlled studies of the analgesic effects of rTMS in patients with NP. Thirty-eight studies were included. Random effect analysis showed effect sizes of -0.66 (95 % CI, -0.87 to -0.46), indicating that real rTMS was better than sham condition in reducing pain (P < 0.001). This comprehensive review indicated that stimulation frequency, intervention site, and location of lesion were important factors affecting the therapeutic effect. The findings of this study may guide clinical decisions and future research.
- Subjects :
- medicine.medical_specialty
Cognitive Neuroscience
medicine.medical_treatment
Analgesic
Cochrane Library
Lesion
Behavioral Neuroscience
Physical medicine and rehabilitation
Humans
Pain Management
Medicine
Cerebral Cortex
business.industry
Therapeutic effect
Chronic pain
medicine.disease
Transcranial Magnetic Stimulation
Transcranial magnetic stimulation
Treatment Outcome
Neuropsychology and Physiological Psychology
Meta-analysis
Neuropathic pain
Neuralgia
Chronic Pain
medicine.symptom
business
Subjects
Details
- ISSN :
- 01497634
- Volume :
- 132
- Database :
- OpenAIRE
- Journal :
- Neuroscience & Biobehavioral Reviews
- Accession number :
- edsair.doi.dedup.....3fdfeff5c826ff41248de370ebcc4471