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Survey for immune complexes in disseminated gonococcal arthritis-dermatitis syndrome
- Source :
- Arthritis and rheumatism. 22(1)
- Publication Year :
- 1979
-
Abstract
- Seventeen patients with characteristic disseminated gonococcal arthritis-dermatitis syndrome were studied for the presence of immune complexes, and circulating gonococcal antigen and antibody. The two immune complex techniques, monoclonal rheumatoid factor assay and cryoglobulin survey, did not reveal any consistent abnormalities. Complement levels (CH50, C″3, C″4) were not consistent with peripheral consumption except in 2 patients with coinciding systemic lupus erythematosus. Gonococcal antibody was detected in 47% of patients when they presented with the syndrome. However, gonococcal antigen was not found in either serum or synovial fluid. These results do not support the hypothesis that circulating immune complexes are involved in the pathogenesis of disseminated gonococcal arthritis-dermatitis syndrome.
- Subjects :
- Pathology
medicine.medical_specialty
Immunology
Embolism
Dermatitis
Antigen-Antibody Complex
Biology
Pathogenesis
Gonorrhea
Immune system
Rheumatology
Antigen
Rheumatoid Factor
Synovial Fluid
medicine
Immunology and Allergy
Synovial fluid
Rheumatoid factor
Humans
Immune Complex Diseases
Lupus Erythematosus, Systemic
Pharmacology (medical)
Cryoglobulins
Antigens, Bacterial
Arthritis
Complement System Proteins
Syndrome
Antibodies, Bacterial
Immune complex
Neisseria gonorrhoeae
Monoclonal
biology.protein
Antibody
Subjects
Details
- ISSN :
- 00043591
- Volume :
- 22
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Arthritis and rheumatism
- Accession number :
- edsair.doi.dedup.....3fede82c1f7028120c4475b807decc0e