PDA-TOLERATE Trial: An Exploratory Randomized Controlled Trial of Treatment of Moderate-to-Large Patent Ductus Arteriosus at 1 Week of Age

Authors :: Ronald I. Clyman
Melissa Liebowitz
Joseph Kaempf
Omer Erdeve
Ali Bulbul
Stellan Håkansson
Johanna Lindqvist
Aijaz Farooqi
Anup Katheria
Jason Sauberan
Jaideep Singh
Kelly Nelson
Andrea Wickremasinghe
Lawrence Dong
Denise C. Hassinger
Susan W. Aucott
Madoka Hayashi
Anne Marie Heuchan
William A. Carey
Matthew Derrick
Erika Fernandez
Meera Sankar
Tina Leone
Jorge Perez
Arturo Serize
Scott Fields
Lora Whitten
Stefanie Rogers
Emel Okulu
Gaffari Tunc
Tayfun Ucar
Ebru Türkoglu Ünal
Jane Steen
Kathy Arnell
Sarah Holtschlag
Michael Schreiber
Caryn Peters
Maureen Gilmore
Lorna McKay
Dianne Carole
Annette Shaw
Malinda Harris
Amy Amsbaugh
Lavonne M. Liedl
Sue Wolf
Avi Groner
Amy Kimball
Jae Kim
Renee Bridge
Ellen Knodel
Chrissy Weng
Magaly Diaz Barbosa
Richard Polin
Marilyn Weindler
Shahab Noori
Jeffrey Reese
Yao Sun
Publication Year :: 2019
Publisher :: eScholarship, University of California, 2019.
Abstract: ObjectiveTo compare early routine pharmacologic treatment of moderate-to-large patent ductus arteriosus (PDA) at the end of week 1 with a conservative approach that requires prespecified respiratory and hemodynamic criteria before treatment can be given.Study designA total of 202 neonates of

Subjects :: Male
medicine.medical_treatment
Indomethacin
Ibuprofen
Reproductive health and childbirth
Conservative Treatment
Low Birth Weight and Health of the Newborn
Pediatrics
law.invention
Randomized controlled trial
law
newborn
Ductus arteriosus
Infant Mortality
Medicine
retinopathy of prematurity
Single-Blind Method
Continuous positive airway pressure
Prospective Studies
Ductus Arteriosus, Patent
Lung
Pediatric
Continuous Positive Airway Pressure
Gestational age
Retinopathy of prematurity
Hematology
premature birth
medicine.anatomical_structure
Treatment Outcome
Premature birth
Anesthesia
Infant, Extremely Premature
Necrotizing enterocolitis
Patent
Female
congenital, hereditary, and neonatal diseases and abnormalities
Clinical Trials and Supportive Activities
Gestational Age
Extremely Premature
TO LEave it alone or Respond And Treat Early) Trial Investigators [PDA-TOLERATE (PDA]
Paediatrics and Reproductive Medicine
Clinical Research
Preterm
bronchopulmonary dysplasia
Humans
Cyclooxygenase Inhibitors
Acetaminophen
necrotizing enterocolitis
business.industry
Infant, Newborn
nutritional and metabolic diseases
Infant
Ductus Arteriosus
Human Movement and Sports Sciences
Perinatal Period - Conditions Originating in Perinatal Period
medicine.disease
Good Health and Well Being
Bronchopulmonary dysplasia
Pediatrics, Perinatology and Child Health
business
Digestive Diseases

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