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Two Cases of Primary Sclerosing Cholangitis Overlapping with Autoimmune Hepatitis in Adults
- Source :
- Internal Medicine
- Publication Year :
- 2017
- Publisher :
- Japanese Society of Internal Medicine, 2017.
-
Abstract
- Overlap syndrome between primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) is extremely rare in Japan. We herein report two adult patients with PSC-AIH overlap syndrome. They were diagnosed with PSC-AIH overlap syndrome based on the findings of endoscopic retrograde cholangiography and liver biopsy, and using the International Autoimmune Hepatitis Group scoring system. In both cases, PSC preceded AIH, and combination therapy with steroid and ursodeoxycholic acid was effective. Because there are few reported cases in Japan, it is important to study more cases to shed light on the clinical and pathological features of PSC-AIH overlap syndrome.
- Subjects :
- Male
medicine.medical_specialty
endocrine system diseases
Combination therapy
Biopsy
Cholangitis, Sclerosing
Case Report
Autoimmune hepatitis
digestive system
Gastroenterology
Primary sclerosing cholangitis
Young Adult
03 medical and health sciences
0302 clinical medicine
immune system diseases
Internal medicine
Internal Medicine
medicine
Humans
Glucocorticoids
Pathological
immunosuppression
autoimmune hepatitis
medicine.diagnostic_test
business.industry
Ursodeoxycholic Acid
digestive, oral, and skin physiology
primary sclerosing cholangitis
Overlap syndrome
Syndrome
General Medicine
Middle Aged
medicine.disease
digestive system diseases
Ursodeoxycholic acid
Hepatitis, Autoimmune
Liver
International Autoimmune Hepatitis Group scoring system
030220 oncology & carcinogenesis
Liver biopsy
Immunology
Endoscopic retrograde cholangiography
Drug Therapy, Combination
030211 gastroenterology & hepatology
Tomography, X-Ray Computed
business
Cholangiography
medicine.drug
Subjects
Details
- ISSN :
- 13497235 and 09182918
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Internal Medicine
- Accession number :
- edsair.doi.dedup.....40d94cbc9b101c178952787e8a71c3d7