Supplementary Figures 1 - 3 from Snail Recruits Ring1B to Mediate Transcriptional Repression and Cell Migration in Pancreatic Cancer Cells

PDF file - 329K, Supplementary Figure 1: Mutation of Ring domains of Ring1A/B proteins does not change their subcellular localization. Supplementary Figure 2: qRT-PCR analysis of the known PRC1 target genes HOXC5 and HOXB4 and Snail target gene Cyclin D2 in PanC1-shLuc and PanC1-shRing1A/B cells. Supplementary Figure 3: Simultaneous depletion of Ring1A and Ring1B results in global decrease of H2AK119 monoubiquitination, and Snail loss of repression on E-cadherin in AsPC1 cells.