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Statistical decision rules concerning synteny or independence between markers
- Source :
- Cytogenetic and Genome Research. 43:132-139
- Publication Year :
- 1986
- Publisher :
- S. Karger AG, 1986.
-
Abstract
- Data on the segregation of human markers in somatic hybrids between permanent rodent cell lines and primary human cells were gathered and statistically analyzed, using various criteria of association. The analysis provides evidence that human chromosomes do not segregate independently in somatic cell hybrids. A statistical decision rule concerning synteny or independence between markers is proposed, and its utility in developing the gene maps of other species by means of somatic cell hybridization is explored.
- Subjects :
- Genetic Markers
Genetics
Models, Genetic
Gene map
Somatic Cell Hybrids
Somatic cell
Statistics as Topic
Chromosome Mapping
Computational biology
Decision rule
Hybrid Cells
Biology
Somatic Cell Hybridization
Mice
Genetic marker
Cricetinae
Animals
Humans
Independence (mathematical logic)
Molecular Biology
Genetics (clinical)
Synteny
Subjects
Details
- ISSN :
- 1424859X and 14248581
- Volume :
- 43
- Database :
- OpenAIRE
- Journal :
- Cytogenetic and Genome Research
- Accession number :
- edsair.doi.dedup.....414f739bbcbddcdcd591a0cfd0961966