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Operational Evaluation of the Effectiveness of Long-lasting Insecticidal Nets on Human-Vector Contact in an African Urban Malaria Context
- Source :
- Open Forum Infectious Diseases
- Publication Year :
- 2020
-
Abstract
- Background Malaria is still a major public health concern in Côte d’Ivoire despite mass distribution of long-lasting insecticidal nets (LLINs) as a key preventive strategy. This study intended to evaluate the operational effectiveness of LLINs on the level of human-vector contact using 1 antibody-based biomarker of exposure to Anopheles in urban areas. Methods This cross-sectional study collected socio-demographic data and use of LLINs from 9 neighborhoods in the city of Bouaké (Côte d’Ivoire). Dry blood spots performed in children aged >6 months and adults were used to evaluate immunoglobulin G (IgG) responses to the Anopheles gSG6-P1 salivary peptide. Results IgG response levels to the salivary peptide were significantly lower in individuals who declared having “always” (n = 270) slept under an LLIN compared with those who had “often” (n = 2087) and “never” (n = 88) slept under an LLIN (P Conclusions The human IgG level to this gSG6-P1 salivary peptide could be a useful tool to evaluate the actual effectiveness of LLINs and help design behavioral change interventions that are crucial for sustaining universal coverage.
- Subjects :
- Long lasting
medicine.medical_specialty
LLIN use
030231 tropical medicine
urban areas
Psychological intervention
Context (language use)
Major Articles
03 medical and health sciences
0302 clinical medicine
salivary biomarkers
Environmental health
parasitic diseases
Anopheles
Medicine
030212 general & internal medicine
biology
business.industry
Public health
medicine.disease
biology.organism_classification
Urban malaria
Infectious Diseases
AcademicSubjects/MED00290
Oncology
Vector (epidemiology)
business
gSG6-P1
Malaria
Subjects
Details
- ISSN :
- 23288957
- Volume :
- 8
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Open forum infectious diseases
- Accession number :
- edsair.doi.dedup.....4168931ce60307551606925662c0ae03