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Investigation of toxic heavy metals content and estimation of potential health risks in Chinese herbal medicine
- Source :
- Journal of hazardous materials. 412
- Publication Year :
- 2020
-
Abstract
- The content of toxic heavy metals (THMs), including lead (Pb), arsenic (As), cadmium (Cd), and mercury (Hg), was determined in a total of 10,245 samples for 279 types of Chinese herbal medicine (CHM) using a validated inductively coupled plasma mass spectrometry method. The exceeding rate (ER) for the four THMs were calculated based on diverse permissible limits (PLs) established by different organizations and national pharmacopeias. Cluster analysis was used to classify the degree risk of THMs contamination according to the calculated ER. Results revealed that Cibotii rhizome, Selaginellae herba, Morindae officinalis radix, Asprellae ilicis radix, and Toxicodendri resina exhibited high-degree risk of Pb contamination. Eckloniae/Laminariae thallus, Spirodelae herba, and Naturalis indigo possessed high-degree risk of As contamination. Tetrapanacis medulla, Centipedae herba, Cyathulae radix, Linderae radix, Meretricis/Cyclinae concha, and Tabanus displayed high-degree risk of Cd contamination. Toxicodendri resina has high-degree risk of Hg contamination. In addition, six types of CHM, including Asprellae ilicis radix, Toxicodendri resina, Eckloniae/Laminariae thallus, Fossilia Ossis Mastodi, Haematitum, and Hedyotidis diffusae herba, may have non-carcinogenic health risk after consumption of raw materials because the calculated hazard quotient and hazard index were over 1.0. In summary, these data provide useful information about THMs contamination in CHM.
- Subjects :
- Environmental Engineering
Health, Toxicology and Mutagenesis
0211 other engineering and technologies
chemistry.chemical_element
02 engineering and technology
010501 environmental sciences
01 natural sciences
Risk Assessment
Arsenic
Metals, Heavy
Environmental Chemistry
Humans
Radix
Waste Management and Disposal
Inductively coupled plasma mass spectrometry
0105 earth and related environmental sciences
021110 strategic, defence & security studies
Cadmium
Traditional medicine
Contamination
Pollution
Hazard quotient
Mercury (element)
Heavy Metal Poisoning
chemistry
Officinalis
Drugs, Chinese Herbal
Subjects
Details
- ISSN :
- 18733336
- Volume :
- 412
- Database :
- OpenAIRE
- Journal :
- Journal of hazardous materials
- Accession number :
- edsair.doi.dedup.....41dd843493ba00fbcf26f4abe6e8fe59