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Molecular Evolution of thePi-taGene Resistant to Rice Blast in Wild Rice (Oryza rufipogon)
- Source :
- Genetics. 179:1527-1538
- Publication Year :
- 2008
- Publisher :
- Oxford University Press (OUP), 2008.
-
Abstract
- Rice blast disease resistance to the fungal pathogen Magnaporthe grisea is triggered by a physical interaction between the protein products of the host R (resistance) gene, Pi-ta, and the pathogen Avr (avirulence) gene, AVR-pita. The genotype variation and resistant/susceptible phenotype at the Pi-ta locus of wild rice (Oryza rufipogon), the ancestor of cultivated rice (O. sativa), was surveyed in 36 locations worldwide to study the molecular evolution and functional adaptation of the Pi-ta gene. The low nucleotide polymorphism of the Pi-ta gene of O. rufipogon was similar to that of O. sativa, but greatly differed from what has been reported for other O. rufipogon genes. The haplotypes can be subdivided into two divergent haplogroups named H1 and H2. H1 is derived from H2, with nearly no variation and at a low frequency. H2 is common and is the ancestral form. The leucine-rich repeat (LRR) domain has a high πnon/πsyn ratio, and the low polymorphism of the Pi-ta gene might have primarily been caused by recurrent selective sweep and constraint by other putative physiological functions. Meanwhile, we provide data to show that the amino acid Ala-918 of H1 in the LRR domain has a close relationship with the resistant phenotype. H1 might have recently arisen during rice domestication and may be associated with the scenario of a blast pathogen–host shift from Italian millet to rice.
- Subjects :
- Magnaporthe
DNA, Plant
Molecular Sequence Data
Locus (genetics)
Investigations
Genes, Plant
Evolution, Molecular
Genotype
Genetics
Magnaporthe grisea
Selection, Genetic
Gene
Plant Diseases
Likelihood Functions
Polymorphism, Genetic
Oryza sativa
Base Sequence
Geography
Models, Genetic
biology
Haplotype
food and beverages
Oryza
biology.organism_classification
Oryza rufipogon
Immunity, Innate
Phenotype
Subjects
Details
- ISSN :
- 19432631
- Volume :
- 179
- Database :
- OpenAIRE
- Journal :
- Genetics
- Accession number :
- edsair.doi.dedup.....41ee5430b4f310151cd818b1c7e5f96b