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Acute Toxicity of Silver Free and Encapsulated in Nanosized Zeolite for Eukaryotic Cells
- Source :
- ACS Applied Materials & Interfaces, ACS Applied Materials & Interfaces, 2017, 9 (16), pp.13849-13854. ⟨10.1021/acsami.7b00265⟩, ACS Applied Materials & Interfaces, Washington, D.C. : American Chemical Society, 2017, 9 (16), pp.13849-13854. ⟨10.1021/acsami.7b00265⟩
- Publication Year :
- 2017
- Publisher :
- American Chemical Society (ACS), 2017.
-
Abstract
- The potential toxicity of encapsulated silver in EMT-type nanosized zeolites on prokaryotic cells, human tumor cell lines from various origins, and primary cultures of neurons and astrocytes was investigated. Silver in cationic form (Ag+) was encapsulated in EMT-type nanosized zeolites via an ion exchange process (Ag+-EMT) and compared with the reduced silver (Ag0) in the zeolite (Ag0-EMT). As reference samples for the toxicity measurements, pure EMT-type zeolite and silver perchlorate were used. Cells were exposed to silver-containing zeolites (50, 100, and 400 μg/mL) for 24 and 48 h. After exposure to Ag+-EMT (50 μg/mL) for 24 h, a loss in cell viability independent of the cell type was observed, ranging from −34.37 ± 23.90% for astrocytes to −99.5 ± 0.24% for U87-MG cells. These results were comparable with the toxicity for silver perchlorate. The Ag0-EMT sample showed lower toxicity on human cell lines in comparison to that of Ag+-EMT. A decrease in cell viability, i.e., −73.46 ± 20.78% and −62.3 ± 17...
- Subjects :
- Cell type
Silver
Materials science
Inorganic chemistry
Metal Nanoparticles
02 engineering and technology
010402 general chemistry
01 natural sciences
chemistry.chemical_compound
Humans
[CHIM]Chemical Sciences
General Materials Science
Zeolite
Ion exchange
Cationic polymerization
021001 nanoscience & nanotechnology
Silver perchlorate
Acute toxicity
0104 chemical sciences
Eukaryotic Cells
HEK293 Cells
chemistry
Cell culture
embryonic structures
Toxicity
Zeolites
0210 nano-technology
Nuclear chemistry
Subjects
Details
- ISSN :
- 19448252 and 19448244
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- ACS Applied Materials & Interfaces
- Accession number :
- edsair.doi.dedup.....420df39171cae6dcd4f4ace68f6778d4