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Electroconvulsive therapy in bipolar depression - effectiveness and prognostic factors
- Source :
- Acta Psychiatrica Scandinavica
- Publication Year :
- 2019
- Publisher :
- Wiley, 2019.
-
Abstract
- Objective: Electroconvulsive therapy (ECT) is used in patients with severe forms of bipolar depression. ECT is effective but not all patients respond. The aim of this study was to determine prognostic factors for response to ECT in patients hospitalized for bipolar depression. Methods: Data were obtained from several national Swedish registers. All patients with bipolar depression treated with ECT in any hospital in Sweden between 2011 and 2016 for whom information about ECT response was available were included (n = 1251). Response was defined as a score on the Clinical Global Impression – Improvement scale of one or two. Univariate and multivariate logistic regression were conducted to investigate associations between socio‐demographic and clinical factors and response. Results: Response was achieved in 80.2% patients. Older age was associated with higher response rate to ECT. Patients with comorbid obsessive‐compulsive disorder or personality disorder, and patients previously treated with lamotrigine had lower response rate. Conclusion: Electroconvulsive therapy for bipolar depression was associated with very high response rates. The strongest prognostic factors were higher age, absence of comorbid obsessive‐compulsive disorder or personality disorder, and less prior pharmacologic treatment. publishedVersion
- Subjects :
- Adult
Male
medicine.medical_specialty
Bipolar Disorder
Adolescent
media_common.quotation_subject
medicine.medical_treatment
Lamotrigine
Logistic regression
behavioral disciplines and activities
electroconvulsive therapy
Psykiatri
Young Adult
03 medical and health sciences
0302 clinical medicine
Electroconvulsive therapy
Internal medicine
Outcome Assessment, Health Care
mental disorders
medicine
Humans
Personality
Registries
Depression (differential diagnoses)
Aged
media_common
Aged, 80 and over
Sweden
Response rate (survey)
Psychiatry
bipolar depression
business.industry
Original Articles
Middle Aged
Prognosis
030227 psychiatry
Psychiatry and Mental health
bipolar disorders
prognosis
Clinical Global Impression
Female
Original Article
Previously treated
business
030217 neurology & neurosurgery
medicine.drug
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Acta Psychiatrica Scandinavica
- Accession number :
- edsair.doi.dedup.....42151d6b3d44e57b33c877648e8f0336