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Borderline resectable pancreatic cancer. Challenges and controversies
- Source :
- Cancer treatment reviews. 68
- Publication Year :
- 2018
-
Abstract
- Pancreatic cancer is a dismal disease with an increasing incidence. Despite the majority of patients are not candidates for curative surgery, a subgroup of patients classified as borderline resectable pancreatic cancer can be selected in whom a sequential strategy of neoadjuvant therapy followed by surgery can provide better outcomes. Multidisciplinary approach and surgical pancreatic expertise are essential for successfully treating these patients. However, the lack of consensual definitions and therapies make the results of studies very difficult to interpret and hard to be implemented in some settings. In this article, we review the challenges of borderline resectable pancreatic cancer, the complexity of its management and controversies and point out where further research and international cooperation for a consensus strategy is urgently needed.
- Subjects :
- medicine.medical_specialty
business.industry
Incidence (epidemiology)
medicine.medical_treatment
General surgery
General Medicine
Disease
030230 surgery
medicine.disease
Pancreatic Neoplasms
03 medical and health sciences
0302 clinical medicine
Oncology
Neoadjuvant treatment
Borderline resectable
030220 oncology & carcinogenesis
Pancreatic cancer
Preoperative Care
medicine
Curative surgery
Humans
Radiology, Nuclear Medicine and imaging
business
Neoadjuvant therapy
Subjects
Details
- ISSN :
- 15321967
- Volume :
- 68
- Database :
- OpenAIRE
- Journal :
- Cancer treatment reviews
- Accession number :
- edsair.doi.dedup.....4233563e12422304b2db37af7144cef6