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Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases
- Source :
- Journal of Clinical Periodontology, 44(S18), S5-S11. Blackwell Munksgaard, JOURNAL OF CLINICAL PERIODONTOLOGY, r-FISABIO: Repositorio Institucional de Producción Científica, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO), Sanz, M, Beighton, D, Curtis, M, Cury, J, Dige, I, Dommisch, H, Ellwood, R, Giacaman, R A, Herrera, D, Herzberg, M, Könönen, E, Marsh, P, Meyle, J, Mira, A, Molina, A, Mombelli, A, Quirynen, M, Reynolds, E, Shapira, L & Zaura, E 2017, ' Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease ', Journal of Clinical Periodontology, bind 44, nr. Suppl. 18, s. S5-S11 . https://doi.org/10.1111/jcpe.12682, r-FISABIO. Repositorio Institucional de Producción Científica, instname, Journal of Clinical Periodontology, Vol. 44 (2017) pp. S5-S11, Journal Of Clinical Periodontology, Artículos CONICYT, CONICYT Chile, instacron:CONICYT, Sanz, M, Beighton, D, Curtis, M A, Cury, J A, Dige, I, Dommisch, H, Ellwood, R, Giacaman, R A, Herrera, D, Herzberg, M C, Könönen, E, Marsh, P D, Meyle, J, Mira, A, Molina, A, Mombelli, A, Quirynen, M, Reynolds, E C, Shapira, L & Zaura, E 2017, ' Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases : Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease ', Journal of Clinical Periodontology, vol. 44, no. S18, pp. S5-S11 . https://doi.org/10.1111/jcpe.12682
- Publication Year :
- 2017
-
Abstract
- Background and Aims: The scope of this working group was to review (1) ecological interactions at the dental biofilm in health and disease, (2) the role of microbial communities in the pathogenesis of periodontitis and caries, and (3) the innate host response in caries and periodontal diseases. Results and Conclusions: A health-associated biofilm includes genera such as Neisseria, Streptococcus, Actinomyces, Veillonella and Granulicatella. Microorganisms associated with both caries and periodontal diseases are metabolically highly specialized and organized as multispecies microbial biofilms. Progression of these diseases involves multiple microbial interactions driven by different stressors. In caries, the exposure of dental biofilms to dietary sugars and their fermentation to organic acids results in increasing proportions of acidogenic and aciduric species. In gingivitis, plaque accumulation at the gingival margin leads to inflammation and increasing proportions of proteolytic and often obligately anaerobic species. The natural mucosal barriers and saliva are the main innate defence mechanisms against soft tissue bacterial invasion. Similarly, enamel and dentin are important hard tissue barriers to the caries process. Given that the present state of knowledge suggests that the aetiologies of caries and periodontal diseases are mutually independent, the elements of innate immunity that appear to contribute to resistance to both are somewhat coincidental.
- Subjects :
- 0301 basic medicine
Veillonella
microbial interactions
Oral Health
symbiosis
Disease
Dental Caries
Microbiology
03 medical and health sciences
Gingivitis
0302 clinical medicine
medicine
caries
Humans
periodontal diseases
Periodontitis
innate host responses
biology
Biofilm
dysbiosis
030206 dentistry
medicine.disease
biology.organism_classification
ddc:617.6
030104 developmental biology
dental biofilm
Oral microbiology
Biofilms
Host-Pathogen Interactions
Periodontics
medicine.symptom
Dysbiosis
Actinomyces
Subjects
Details
- Language :
- English
- ISSN :
- 03036979
- Volume :
- 44
- Issue :
- S18
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Periodontology
- Accession number :
- edsair.doi.dedup.....423afd701d64c1ea313b9d431bfd72d9
- Full Text :
- https://doi.org/10.1111/jcpe.12682