Back to Search Start Over

Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases

Authors :
Jaime Aparecido Cury
Michael A. Curtis
Mariano Sanz
David Herrera
Irene Dige
Marc Quirynen
Mark C. Herzberg
Joerg Meyle
Andrea Mombelli
Rodrigo A. Giacaman
Egija Zaura
David Beighton
Eric C. Reynolds
Henrik Dommisch
Eija Könönen
Lior Shapira
Roger Ellwood
Philip Marsh
Alex Mira
Ana Molina
Preventieve tandheelkunde (OII, ACTA)
Preventive Dentistry
Source :
Journal of Clinical Periodontology, 44(S18), S5-S11. Blackwell Munksgaard, JOURNAL OF CLINICAL PERIODONTOLOGY, r-FISABIO: Repositorio Institucional de Producción Científica, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO), Sanz, M, Beighton, D, Curtis, M, Cury, J, Dige, I, Dommisch, H, Ellwood, R, Giacaman, R A, Herrera, D, Herzberg, M, Könönen, E, Marsh, P, Meyle, J, Mira, A, Molina, A, Mombelli, A, Quirynen, M, Reynolds, E, Shapira, L & Zaura, E 2017, ' Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease ', Journal of Clinical Periodontology, bind 44, nr. Suppl. 18, s. S5-S11 . https://doi.org/10.1111/jcpe.12682, r-FISABIO. Repositorio Institucional de Producción Científica, instname, Journal of Clinical Periodontology, Vol. 44 (2017) pp. S5-S11, Journal Of Clinical Periodontology, Artículos CONICYT, CONICYT Chile, instacron:CONICYT, Sanz, M, Beighton, D, Curtis, M A, Cury, J A, Dige, I, Dommisch, H, Ellwood, R, Giacaman, R A, Herrera, D, Herzberg, M C, Könönen, E, Marsh, P D, Meyle, J, Mira, A, Molina, A, Mombelli, A, Quirynen, M, Reynolds, E C, Shapira, L & Zaura, E 2017, ' Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases : Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease ', Journal of Clinical Periodontology, vol. 44, no. S18, pp. S5-S11 . https://doi.org/10.1111/jcpe.12682
Publication Year :
2017

Abstract

Background and Aims: The scope of this working group was to review (1) ecological interactions at the dental biofilm in health and disease, (2) the role of microbial communities in the pathogenesis of periodontitis and caries, and (3) the innate host response in caries and periodontal diseases. Results and Conclusions: A health-associated biofilm includes genera such as Neisseria, Streptococcus, Actinomyces, Veillonella and Granulicatella. Microorganisms associated with both caries and periodontal diseases are metabolically highly specialized and organized as multispecies microbial biofilms. Progression of these diseases involves multiple microbial interactions driven by different stressors. In caries, the exposure of dental biofilms to dietary sugars and their fermentation to organic acids results in increasing proportions of acidogenic and aciduric species. In gingivitis, plaque accumulation at the gingival margin leads to inflammation and increasing proportions of proteolytic and often obligately anaerobic species. The natural mucosal barriers and saliva are the main innate defence mechanisms against soft tissue bacterial invasion. Similarly, enamel and dentin are important hard tissue barriers to the caries process. Given that the present state of knowledge suggests that the aetiologies of caries and periodontal diseases are mutually independent, the elements of innate immunity that appear to contribute to resistance to both are somewhat coincidental.

Details

Language :
English
ISSN :
03036979
Volume :
44
Issue :
S18
Database :
OpenAIRE
Journal :
Journal of Clinical Periodontology
Accession number :
edsair.doi.dedup.....423afd701d64c1ea313b9d431bfd72d9
Full Text :
https://doi.org/10.1111/jcpe.12682