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Complications of Evans' syndrome in an infant with hereditary spherocytosis: a case report
- Source :
- Journal of Hematology & Oncology, Journal of Hematology & Oncology, Vol 2, Iss 1, p 40 (2009)
- Publication Year :
- 2009
- Publisher :
- Springer Science and Business Media LLC, 2009.
-
Abstract
- Hereditary spherocytosis (HS) is a genetic disorder of the red blood cell membrane clinically characterized by anemia, jaundice and splenomegaly. Evans' syndrome is a clinical syndrome characterized by autoimmune hemolytic anemia (AIHA) accompanied by immune thrombocytopenic purpura (ITP). It results from a malfunction of the immune system that produces multiple autoantibodies targeting at least red blood cells and platelets. HS and Evans' syndrome have different mechanisms of pathophysiology one another. We reported the quite rare case of an infant who had these diseases concurrently. Possible explanations of the unexpected complication are discussed.
- Subjects :
- Male
Cancer Research
Evans syndrome
Anemia
Case Report
Spherocytosis, Hereditary
lcsh:RC254-282
Hereditary spherocytosis
hemic and lymphatic diseases
Humans
Medicine
Molecular Biology
Purpura, Thrombocytopenic, Idiopathic
lcsh:RC633-647.5
Platelet Count
business.industry
Genetic disorder
Infant
lcsh:Diseases of the blood and blood-forming organs
Syndrome
Hematology
Jaundice
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
medicine.disease
Thrombocytopenic purpura
Red blood cell
medicine.anatomical_structure
Oncology
Immunology
Anemia, Hemolytic, Autoimmune
medicine.symptom
Autoimmune hemolytic anemia
business
Subjects
Details
- ISSN :
- 17568722
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of Hematology & Oncology
- Accession number :
- edsair.doi.dedup.....425ca1d16c9c57b1a10f2684267c0f37