Additional file 1 of Establishment and evaluation of glucose-modified nanocomposite liposomes for the treatment of cerebral malaria

Additional file 1: Figure S1 The chemical structure of 3-(11-bromoundecanoate)-cholesterol. Figure S2 Snapshots showing the spontaneous self-assembly of PLPC into a bilayer. The PLPC and undecane-glucose conjugate is depicted as yellow and cyan respectively, blue is nitrogen atom in phospholipids, red is oxygen atom in conjugates. Note that water molecules are not shown. Figure S3 Snapshots showing the spontaneous self-assembly of PLPC into a bilayer. The PLPC and arbutin is depicted as yellow and cyan respectively, blue is nitrogen atom in phospholipids, red is oxygen atom in conjugates. Note that water molecules are not shown. Figure S4 Snapshots showing the spontaneous self-assembly of PLPC into a bilayer. The PLPC and cholesterol is depicted as yellow and cyan respectively, blue is nitrogen atom in phospholipids, red is oxygen atom in conjugates. Note that water molecules are not shown. Figure S5 1H NMR spectrum of 3-(11-bromoundecanoate)-cholesterol. Figure S6 13C NMR spectrum of 3-(11-bromoundecanoate)-cholesterol. Figure S7 Infrared spectrum of 3-(11-bromoundecanoate)-cholesterol. Figure S8 1H NMR spectrum of cholesterol-undecanoate-glucose conjugate. Figure S9 13C NMR spectrum of cholesterol-undecanoate-glucose conjugate. Figure S10 COSY spectrum of Cholesterol-undecanoate-glucose conjugate. Figure S11 HSQC spectrum of Cholesterol-undecanoate-glucose conjugate. Figure S12 HMBC spectrum of Cholesterol-undecanoate-glucose conjugate. Figure S13 ESI mass spectrum of Cholesterol-undecanoate-glucose conjugate. Figure S14 Infrared spectrum of Cholesterol-undecanoate-glucose conjugate. Figure S15 is TEM image of iv-ART/TMP@lipoBX Figure S16 Particle size distribution of iv-ART/TMP@lipoBX. Figure S17 DSC spectrum of iv-ART/TMP@lipoBX.