Visible light-mediated difluoroalkylation of electron-deficient alkenes

Authors :: Jinbo Hu
Alexander D. Dilman
Vitalij V. Levin
Vyacheslav I. Supranovich
Marina I. Struchkova
Source :: Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1637-1641 (2018), Beilstein Journal of Organic Chemistry
Publication Year :: 2018
Publisher :: Beilstein Institut, 2018.
Abstract: A method for the reductive difluoroalkylation of electron-deficient alkenes using 1,1-difluorinated iodides mediated by irradiation with blue light is described. The reaction involves radical addition of 1,1-difluorinated radicals at the double bond followed by hydrogen atom transfer from sodium cyanoborohydride.