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MOESM1 of Global impact of somatic structural variation on the DNA methylome of human cancers

Authors :
Yiqun Zhang
Lixing Yang
Kucherlapati, Melanie
Hadjipanayis, Angela
Pantazi, Angeliki
Bristow, Christopher
Eunjung Lee
Harshad Mahadeshwar
Jiabin Tang
Jianhua Zhang
Sahil Seth
Lee, Semin
Xiaojia Ren
Xingzhi Song
Huandong Sun
Seidman, Jonathan
Lovelace Luquette
Ruibin Xi
Chin, Lynda
Protopopov, Alexei
Park, Peter
Kucherlapati, Raju
Creighton, Chad
Publication Year :
2019
Publisher :
figshare, 2019.

Abstract

Additional file 1: Figure S1. Related to Fig. 1. Batch effects correction involving RNA-seq and DNA copy number alteration (CNA) datasets. Figure S2. related to Fig. 2. Additional information regarding the top set of genes with altered expression associated with nearby SSV breakpoint by distance metric method. Figure S3. related to Fig. 2. Addition information regarding genes with altered expression associated with nearby SSV breakpoint. Figure S4. related to Fig. 3. Additional information on genes with altered expression associated with nearby SSV breakpoint according to cancer type. Figure S5. related to Fig. 4. Additional information regarding the top set of CGIs with altered methylation associated with nearby SSV breakpoint by distance metric method. Figure S6. related to Fig. 4. Additional information on CGIs with altered DNA methylation associated with nearby SSV breakpoint. Figure S7. related to Fig. 5. DNA methylation patterns by cancer type and tissue type. Figure S8. related to Fig. 6. Additional information regarding global molecular alterations associated with the overall burden of structural variation across cancers.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....42f6fc0a5609f13db076e64d322d5dc0
Full Text :
https://doi.org/10.6084/m9.figshare.9980405