Back to Search
Start Over
Characterization of intraocular pressure increases and management strategies following treatment with fluocinolone acetonide intravitreal implants in the fame trials
- Publication Year :
- 2016
- Publisher :
- Slack Incorporated, 2016.
-
Abstract
- BACKGROUND AND OBJECTIVE: To compare elevated intraocular pressure (IOP) management and outcomes among patients with diabetic macular edema who received fluocinolone acetonide (FAc) implants versus sham-control treatment and explore the prior ocular steroid exposure impact on IOP outcomes. PATIENTS AND METHODS: Best-corrected visual acuity (BCVA) was measured using Early Treatment Diabetic Retinopathy Study charts or electronic VA testers. Goldmann applanation tonometry was used to measure IOP. RESULTS: Elevated IOP was more common in FAc-versus sham control-treated patients. Medication, and less often trabeculoplasty or surgery, was used to lower IOP without affecting VA outcomes. No patient treated with 0.2 µg/day FAc who received prior ocular steroid required IOP-lowering surgery. CONCLUSION: Elevated IOP may occur following FAc implant receipt; however, in the present study, it was manageable and did not impact vision outcomes. Patients previously treated with ocular steroid did not require IOP-lowering surgery following 0.2 µg/day FAc implant administration. [ Ophthalmic Surg Lasers Imaging Retina. 2016;47:426–435.]
- Subjects :
- Male
medicine.medical_specialty
Intraocular pressure
Time Factors
Visual acuity
Trabeculoplasty
genetic structures
medicine.medical_treatment
Diabetic macular edema
Visual Acuity
Trabeculectomy
Macular Edema
Goldmann applanation tonometry
Tonometry, Ocular
03 medical and health sciences
0302 clinical medicine
Fluocinolone acetonide
Ophthalmology
medicine
Humans
Glucocorticoids
Antihypertensive Agents
Intraocular Pressure
Drug Implants
Diabetic Retinopathy
Dose-Response Relationship, Drug
business.industry
Disease Management
Diabetic retinopathy
Middle Aged
medicine.disease
Surgery
eye diseases
Vitreous Body
Treatment Outcome
Fluocinolone Acetonide
Practice Guidelines as Topic
030221 ophthalmology & optometry
Female
Ocular Hypertension
sense organs
Implant
medicine.symptom
business
030217 neurology & neurosurgery
Follow-Up Studies
medicine.drug
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....441665605b238cc9c47db60662d90f91