Back to Search
Start Over
Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events
- Source :
- Science
- Publication Year :
- 2020
- Publisher :
- American Association for the Advancement of Science (AAAS), 2020.
-
Abstract
- Phylogenetics of superspreading One important characteristic of coronavirus epidemiology is the occurrence of superspreading events. These are marked by a disproportionate number of cases originating from often-times asymptomatic individuals. Using a rich sequence dataset from the early stages of the Boston outbreak, Lemieux et al. identified superspreading events in specific settings and analyzed them phylogenetically (see the Perspective by Alizon). Using ancestral trait inference, the authors identified several importation events, further investigated the context and contribution of particular superspreading events to the establishment of local and wider SARS-CoV-2 transmission, and used viral phylogenies to describe sustained transmission. Science , this issue p. eabe3261 ; see also p. 574
- Subjects :
- 0301 basic medicine
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Genome, Viral
law.invention
Disease Outbreaks
03 medical and health sciences
0302 clinical medicine
law
Vulnerable population
Humans
030212 general & internal medicine
Phylogeny
Multidisciplinary
Phylogenetic tree
Extramural
SARS-CoV-2
COVID-19
030104 developmental biology
Transmission (mechanics)
Geography
Evolutionary biology
Epidemiological Monitoring
Skilled Nursing Facility
Boston
Subjects
Details
- Language :
- English
- ISSN :
- 10959203 and 00368075
- Database :
- OpenAIRE
- Journal :
- Science
- Accession number :
- edsair.doi.dedup.....45a098c0e7d41c24a05e6f49c914d778
- Full Text :
- https://doi.org/10.1126/science.abe3261