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Efficacy and safety of CT-guided percutaneous pulsed radiofrequency treatment of the Gasserian ganglion in patients with medically intractable idiopathic trigeminal neuralgia
- Source :
- Journal of Pain Research
- Publication Year :
- 2018
- Publisher :
- Informa UK Limited, 2018.
-
Abstract
- Meng Lan,* Jia Zipu,* Shen Ying, Ren Hao, Luo Fang Department of Anesthesiology and Pain Management, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China*These authors contributed equally to this workBackground: There is a lack of prospective studies for the long-term results of percutaneous pulsed radiofrequency (PRF) of the Gasserian ganglion in the treatment of patients with medically refractory trigeminal neuralgia (TN).Methods and results: We prospectively observed the outcomes of 28 idiopathic TN patients (between July 2013 and July 2016) who received CT-guided percutaneous PRF treatment of the Gasserian ganglion. All of the patients had stopped responding to drug therapy before PRF treatment. The effective treatment standard was a reduction in the pain numeric rating scale (NRS) by≥50% after the procedure. The postoperative NRS score decreased gradually from preoperative 7.6±0.8 months to 1.5±2.4, 0.2±0.4, 0.2±0.4, 0.1±0.4, and 0.1±0.4 at 1, 3, and 6 months and 1 and 2 years after the PRF treatment. The response rates at 1, 3, and 6 months were 85.7%, and the rates at 12 months and 2 years were maintained at 78.6%. No serious side effects were observed.Conclusion: CT-guided PRF invention is an effective and safe technique for medically intractable idiopathic TN patients. This minimally invasive alternative treatment has the potential as a first-line therapy for TN. Keywords: trigeminal neuralgia, pulsed radiofrequency, efficacy, safety
- Subjects :
- safety
medicine.medical_specialty
Percutaneous
efficacy
pulsed radiofrequency
03 medical and health sciences
0302 clinical medicine
Pharmacotherapy
Refractory
030202 anesthesiology
Trigeminal neuralgia
Medicine
Case Series
Journal of Pain Research
Prospective cohort study
trigeminal neuralgia
Pulsed radiofrequency
business.industry
medicine.disease
Surgery
Ganglion
Anesthesiology and Pain Medicine
medicine.anatomical_structure
Pulsed Radiofrequency Treatment
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 11787090
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Journal of Pain Research
- Accession number :
- edsair.doi.dedup.....45e3c0f8352a6aa279300e6d6f137341