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The dual-function of bioactive peptides derived from oyster (Crassostrea gigas) proteins hydrolysates
- Source :
- Food Science and Human Wellness. 12:1609-1617
- Publication Year :
- 2023
- Publisher :
- Tsinghua University Press, 2023.
-
Abstract
- Oysters (Crassostrea gigas) have a wide range of functionality due to their nutritional and bioactive components. However, the bioactive peptides of oyster proteins are rarely reported, particularly their anti-diabetes effects and antioxidants. Oyster proteins were extracted from fresh oysters using phosphate-buffered saline and simulated gastrointestinal digestion was performed. The degree of hydrolysis (DH), structural characterization, molecular weight (Mw) distribution, free amino acid, anti-diabetic activity, and antioxidant activity were studied during in vitro simulated gastrointestinal digestion. The results showed that the alpha-glucosidase inhibitory activity, alpha-amylase inhibitory activity, DPPH radical scavenging activity, and ABTS radical scavenging activity of the oyster protein gastrointestinal digest were increased (P < 0.05) from 0 to 33.96%, from 9.17% to 44.22%, from 9.01 mu g trolox/mg protein to 18.48 mu g trolox/mg protein, and from 21.44 mu g trolox/mg protein to 56.21 mu g trolox/mg protein, respectively. Additionally, the DH, beta-turn structure, fluorescence intensity, free amino acid, and short peptide content (Mw < 1 000 Da) increased in the simulated gastrointestinal digestion. These results indicate that the digestive hydrolysates obtained from oyster proteins could be used as natural anti-diabetic and antioxidant agents.
Details
- ISSN :
- 22134530
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Food Science and Human Wellness
- Accession number :
- edsair.doi.dedup.....4667f82d9093b5e1ccbdd8d4e7f39552