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Verteporfin Photodynamic Therapy for Subfoveal Choroidal Neovascularization in Pathologic Myopia: A 12-Month Retrospective Review
- Source :
- Scopus-Elsevier
- Publication Year :
- 2008
- Publisher :
- SAGE Publications, 2008.
-
Abstract
- Purpose. To evaluate the visual outcome of patients with subfoveal choroidal neovascularization (CNV) secondary to pathologic myopia treated with verteporfin photodynamic therapy (PDT-V) and to verify the predictive role of visual and angiographic parameters. Methods. This is a retrospective, interventional, consecutive case series study of subjects with subfoveal CNV secondary to pathologic myopia. All patients received PDT-V according to VIP guidelines. A complete ophthalmologic evaluation was performed on all patients and included best-corrected visual acuity (BCVA), fundus examination, and fluorescein angiography (FA, IMAGEnet System, Topcon Corp., Japan). CNV size (mm2) was directly measured on the early phase of the angiogram using the software included with the IMAGEnet package. All checks were scheduled at 3-month intervals for a period of 1 year. A review of medical and angiographic records was performed and assessed throughout a 12-month follow-up period. Results. A total of 62 patients (62 eyes) were examined. Best-corrected visual acuity (BCVA) moderately decreased without reaching a statistically noticeable level throughout the followup; reduction in lesion size reached a significant level at the second checkup. A significant correlation between higher baseline BCVA and better final visual outcome was detected. Conclusions. Standardized PDT-V minimizes central vision deterioration in patients with CNV secondary to pathologic myopia. Better BCVA at presentation represents a good predictive sign. © Wichtig Editore, 2008.
- Subjects :
- Adult
Male
Fovea Centralis
medicine.medical_specialty
Porphyrins
Visual acuity
genetic structures
medicine.medical_treatment
Visual Acuity
Photodynamic therapy
Fundus (eye)
03 medical and health sciences
0302 clinical medicine
PDT
Ophthalmology
Pathologic myopia
Myopia
medicine
Humans
subfoveal choroidal neovascualrization
Fluorescein Angiography
Aged
Retrospective Studies
Aged, 80 and over
Photosensitizing Agents
medicine.diagnostic_test
business.industry
myopia
Verteporfin
General Medicine
Consecutive case series
Middle Aged
Fluorescein angiography
Choroidal Neovascularization
eye diseases
Treatment Outcome
Choroidal neovascularization
Photochemotherapy
Myopia, Degenerative
030221 ophthalmology & optometry
Female
sense organs
medicine.symptom
business
030217 neurology & neurosurgery
medicine.drug
Subjects
Details
- ISSN :
- 17246016 and 11206721
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- European Journal of Ophthalmology
- Accession number :
- edsair.doi.dedup.....46a0426e3efea8ddbcca2d0c8836a3a2