Sustained viral suppression and immune recovery in HIV type 1-infected children after 4 years of highly active antiretroviral therapy

Authors :: David M. Burger
Gwenda Verweel
Pieter L. A. Fraaij
Corry M.R. Weemaes
Annemarie M. C. van Rossum
Ronald de Groot
Nico G. Hartwig
Ellen G. van Lochem
Martin Schutten
Pediatrics
Immunology
Virology
Source :: Clinical Infectious Diseases, 40(4), 604-608. Oxford University Press, Clinical Infectious Diseases, 40, 4, pp. 604-8, Clinical Infectious Diseases, 40, 604-8
Publication Year :: 2005
Publisher :: Oxford University Press, 2005.
Abstract: Contains fulltext : 48438.pdf (Publisher’s version ) (Open Access) We report the data from a long-term study of 31 human immunodeficiency virus type 1 (HIV-1)-infected children who were treated with highly active antiretroviral therapy. A high proportion of the children had undetectable HIV-1 RNA levels. CD4+ T cell counts recovered and remained stable. Adverse events were observed frequently but were mostly mild.

Subjects :: Male
Microbiology (medical)
Time Factors
Adolescent
Infectious diseases and international health [NCEBP 13]
HIV Infections
Auto-immunity, transplantation and immunotherapy [N4i 4]
Virus
Cohort Studies
Invasive mycoses and compromised host [N4i 2]
Cognitive neurosciences [UMCN 3.2]
Acquired immunodeficiency syndrome (AIDS)
SDG 3 - Good Health and Well-being
Antiretroviral Therapy, Highly Active
Immunopathology
medicine
Humans
Prospective Studies
Child
Adverse effect
Sida
biology
business.industry
Poverty-related infectious diseases [N4i 3]
medicine.disease
biology.organism_classification
Virology
CD4 Lymphocyte Count
Pathogenesis and modulation of inflammation [N4i 1]
Treatment Outcome
Infectious Diseases
Child, Preschool
Lentivirus
Immunology
HIV-1
RNA, Viral
Female
Microbial pathogenesis and host defense [UMCN 4.1]
Viral disease
business
Viral load

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