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Arterial ischemic stroke: experience in Chinese children
- Source :
- Pediatric neurology. 38(3)
- Publication Year :
- 2007
-
Abstract
- The aim of this study was to review cases of pediatric arterial ischemic stroke among Chinese subjects and thereby evaluate risk factors, clinical and neuroimaging features, and treatment, to establish a reasonable guideline for assessment and management of the disease. Between 1996 and 2006, 157 children (male:female ratio, 1.4:1) with arterial ischemic stroke were identified at Beijing Children's Hospital. The median age at stroke was 32 months (range, 4-192). Among patients with determined etiology, infections (12.1%), moyamoya disease (12.1%), and trauma (10.8%) were the most common. In 51 patients, there were no obvious risk factors (32.5%). Hemiplegia was the most common presenting feature (81.5%). The region of left middle cerebral artery was most frequently affected (36.3%), followed by the right middle cerebral artery (29.9%). Of the 157 patients, 56 were treated by intravenous thrombolytic agents (35.7%), all but one of them successfully (the one exception involving hemorrhagic complication). Randomized controlled trials are needed to establish primary prevention, acute treatment, and secondary prevention of pediatric ischemic stroke.
- Subjects :
- Male
medicine.medical_specialty
Middle Cerebral Artery
Adolescent
Hemiplegia
Pediatrics
Brain Ischemia
Brain ischemia
Developmental Neuroscience
Asian People
medicine.artery
Internal medicine
medicine
Humans
Thrombolytic Therapy
Moyamoya disease
Child
Stroke
Retrospective Studies
Vascular disease
business.industry
Cerebral infarction
Infant
Retrospective cohort study
medicine.disease
Surgery
Neurology
Child, Preschool
Pediatrics, Perinatology and Child Health
Middle cerebral artery
Etiology
Female
Neurology (clinical)
business
Subjects
Details
- ISSN :
- 08878994
- Volume :
- 38
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Pediatric neurology
- Accession number :
- edsair.doi.dedup.....46a9551ac9b04f8917ff3c2eafc141a3