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The Association between Macular Thickness and Axial Length in Myopic Eyes
- Source :
- BioMed Research International, Vol 2019 (2019), BioMed Research International
- Publication Year :
- 2019
- Publisher :
- Hindawi Limited, 2019.
-
Abstract
- Purpose. To investigate the relationship between macular thickness and axial length (AL) in myopic eyes. Methods. We included 441 myopic eyes in this study and measured macular thickness at the fovea and in other macular regions, using optical coherence tomography. We got thickness difference indices (TDIs) which by definition are the values of thickness difference obtained by subtracting the foveal thickness from that of each macula sector to evaluate macular contour. We then analyzed the relationships between AL and foveal thickness and AL and the TDIs of each macular sector. Results. In polynomial regression analyses, foveal thickness slope was relatively flat up to an AL of 25.5 mm and began to rise from 25.5–26.0 mm. The TDIs were also relatively flat up to AL of 25.5mm and started to show steepened negative slopes from around AL of 25.5 mm. When grouping myopia participants as high myopia or non-high myopia based on AL of 25.5mm, all macular indices of the high myopia group showed significant correlation with AL (all p values Conclusions. Average macular thickness profiles showed that appreciable changes started at an AL of 25.5mm.
- Subjects :
- Adult
Male
0301 basic medicine
Fovea Centralis
medicine.medical_specialty
genetic structures
Article Subject
lcsh:Medicine
Foveal thickness
General Biochemistry, Genetics and Molecular Biology
03 medical and health sciences
0302 clinical medicine
Optical coherence tomography
Ophthalmology
Myopia
Humans
Medicine
Polynomial regression
General Immunology and Microbiology
medicine.diagnostic_test
business.industry
lcsh:R
High myopia
General Medicine
Axial length
eye diseases
030104 developmental biology
030221 ophthalmology & optometry
Female
sense organs
business
Tomography, Optical Coherence
Research Article
Subjects
Details
- ISSN :
- 23146141 and 23146133
- Volume :
- 2019
- Database :
- OpenAIRE
- Journal :
- BioMed Research International
- Accession number :
- edsair.doi.dedup.....46cc30cce3fc46a4a6de509d45e3a5f2